Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

A review on the design of hydrogels with different stiffness and their effects on tissue repair

T Luo, B Tan, L Zhu, Y Wang, J Liao - Frontiers in bioengineering and …, 2022 - frontiersin.org
Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …

One‐Step Soaking Strategy toward Anti‐Swelling Hydrogels with a Stiff “Armor”

X Dou, H Wang, F Yang, H Shen, X Wang… - Advanced …, 2023 - Wiley Online Library
Double‐network (DN) hydrogels consisting of noncovalent interacting networks are highly
desired due to their well‐controlled compositions and environmental friendliness, but the …

Hydrogels with reversible mechanics to probe dynamic cell microenvironments

AM Rosales, SL Vega, FW DelRio… - Angewandte Chemie …, 2017 - Wiley Online Library
The relationship between ECM mechanics and cell behavior is dynamic, as cells remodel
and respond to changes in their local environment. Most in vitro substrates are static and …

Stiffening hydrogels to probe short-and long-term cellular responses to dynamic mechanics

M Guvendiren, JA Burdick - Nature communications, 2012 - nature.com
Biological processes are dynamic in nature, and growing evidence suggests that matrix
stiffening is particularly decisive during development, wound healing and disease; yet …

Structures and synthesis of zwitterionic polymers

A Laschewsky - Polymers, 2014 - mdpi.com
The structures and synthesis of polyzwitterions (“polybetaines”) are reviewed, emphasizing
the literature of the past decade. Particular attention is given to the general challenges …

3D spatiotemporal mechanical microenvironment: a hydrogel‐based platform for guiding stem cell fate

Y Ma, M Lin, G Huang, Y Li, S Wang, G Bai… - Advanced …, 2018 - Wiley Online Library
Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …

Engineering biomaterials to tailor the microenvironment for macrophage–endothelium interactions

Y Guan, L Racioppi, S Gerecht - Nature Reviews Materials, 2023 - nature.com
Macrophages and endothelial cells (ECs) have essential roles in physiological and
pathological conditions by regulating inflammation, vascularization and tissue remodelling …

Swelling-strengthening hydrogels by embedding with deformable nanobarriers

F Wu, Y Pang, J Liu - Nature Communications, 2020 - nature.com
Biological tissues, such as muscle, can increase their mechanical strength after swelling due
to the existence of many biological membrane barriers that can regulate the transmembrane …