[HTML][HTML] Endocrine disrupting chemicals' effects in children: what we know and what we need to learn?

B Predieri, L Iughetti, S Bernasconi… - International journal of …, 2022 - mdpi.com
Thousands of natural or manufactured chemicals were defined as endocrine-disrupting
chemicals (EDCs) because they can interfere with hormone activity and the endocrine …

[HTML][HTML] Fish toxicity testing for identification of thyroid disrupting chemicals

ZC Dang, M Arena, A Kienzler - Environmental Pollution, 2021 - Elsevier
Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of
endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals …

A pragmatic approach to adverse outcome pathway development and evaluation

T Svingen, DL Villeneuve, D Knapen… - Toxicological …, 2021 - academic.oup.com
The adverse outcome pathway (AOP) framework provides a practical means for organizing
scientific knowledge that can be used to infer cause-effect relationships between stressor …

[HTML][HTML] Bisphenol A alters retinal morphology, visually guided behavior, and thyroid hormone levels in zebrafish larvae

SN Volz, R Poulsen, M Hansen, H Holbech - Chemosphere, 2024 - Elsevier
Bisphenols are industrial chemicals that are produced in large quantities and have been
detected in all parts of the environment as well as in a multitude of different organisms …

[HTML][HTML] Emerging concepts and opportunities for endocrine disruptor screening of the non-EATS modalities

CJ Martyniuk, R Martínez, L Navarro-Martín… - Environmental …, 2022 - Elsevier
Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and involve
diverse chemical-receptor interactions that can perturb hormone signaling. The Organization …

Endocrine disruption in teleosts and amphibians is mediated by anthropogenic and natural environmental factors: implications for risk assessment

W Kloas, M Stöck, I Lutz… - … Transactions of the …, 2024 - royalsocietypublishing.org
Environmental variation in the Anthropocene involves several factors that interfere with
endocrine systems of wildlife and humans, presenting a planetary boundary of still unknown …

Reversibility of Thyroid Hormone System–Disrupting Effects on Eye and Thyroid Follicle Development in Zebrafish (Danio rerio) Embryos

P Pannetier, R Poulsen, L Gölz… - Environmental …, 2023 - academic.oup.com
Early vertebrate development is partially regulated by thyroid hormones (THs).
Environmental pollutants that interact with the TH system (TH system–disrupting chemicals …

Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans

N Sharma, V Kumar, S Vimal, M Umesh… - Environmental …, 2024 - Elsevier
Endocrine disrupting chemicals or carcinogens have been known for decades for their
endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they …

Impact of endocrine disrupting chemicals on neurodevelopment: the need for better testing strategies for endocrine disruption-induced developmental neurotoxicity

A Cediel-Ulloa, DL Lupu, Y Johansson… - Expert Review of …, 2022 - Taylor & Francis
Introduction Brain development is highly dependent on hormonal regulation. Exposure to
chemicals disrupting endocrine signaling has been associated with neurodevelopmental …

AOP report: Thyroperoxidase inhibition leading to altered visual function in fish via altered retinal layer structure

L Gölz, L Baumann, P Pannetier… - Environmental …, 2022 - academic.oup.com
Thyroid hormones (THs) are involved in the regulation of many important physiological and
developmental processes, including vertebrate eye development. Thyroid hormone system …