Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W **ao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Recent developments in the inhibition of bacterial adhesion as promising anti-virulence strategy

C Pecoraro, D Carbone, B Parrino… - International Journal of …, 2023 - mdpi.com
Infectious diseases caused by antimicrobial-resistant strains have become a serious threat
to global health, with a high social and economic impact. Multi-resistant bacteria exhibit …

Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM

R Wu, JW Bakelar, K Lundquist, Z Zhang… - Nature …, 2021 - nature.com
In Gram-negative bacteria, the biogenesis of β-barrel outer membrane proteins is mediated
by the β-barrel assembly machinery (BAM). The mechanism employed by BAM is complex …

Immune-microbiota interplay and colonization resistance in infection

A Leshem, T Liwinski, E Elinav - Molecular cell, 2020 - cell.com
Commensal microbial communities inhabit biological niches in the mammalian host, where
they impact the host's physiology through induction of" colonization resistance" against …

Biogeochemistry of Earth before exoenzymes

N Mahmoudi, AD Steen, GP Halverson… - Nature …, 2023 - nature.com
Microorganisms that transform and oxidize organic material (that is, heterotrophs) play a
fundamental role in the geochemical cycling of key elements in the ocean. Through their …

Pathogenicity and virulence of Acinetobacter baumannii: Factors contributing to the fitness in healthcare settings and the infected host

M Lucidi, D Visaggio, A Migliaccio, G Capecchi… - Virulence, 2024 - Taylor & Francis
Acinetobacter baumannii is a common cause of healthcare-associated infections and
hospital outbreaks, particularly in intensive care units. Much of the success of A. baumannii …

Gut biofilms: Bacteroides as model symbionts to study biofilm formation by intestinal anaerobes

N Béchon, JM Ghigo - FEMS microbiology reviews, 2022 - academic.oup.com
Bacterial biofilms are communities of adhering bacteria that express distinct properties
compared to their free-living counterparts, including increased antibiotic tolerance and …

[HTML][HTML] Secrete or perish: the role of secretion systems in Xanthomonas biology

CE Alvarez-Martinez, GG Sgro, GG Araujo… - Computational and …, 2021 - Elsevier
Bacteria of the Xanthomonas genus are mainly phytopathogens of a large variety of crops of
economic importance worldwide. Xanthomonas spp. rely on an arsenal of protein effectors …

Pathogenic arsenal of Pseudomonas aeruginosa: an update on virulence factors

VV Veetilvalappil, A Manuel, JM Aranjani… - Future …, 2022 - Taylor & Francis
The emergence of Pseudomonas aeruginosa as a potential threat in persistent infections
can be attributed to the plethora of virulence factors expressed by it. This review discusses …

Phylogenetic classification and functional review of autotransporters

KR Clarke, L Hor, A Pilapitiya, J Luirink… - Frontiers in …, 2022 - frontiersin.org
Autotransporters are the core component of a molecular nano-machine that delivers cargo
proteins across the outer membrane of Gram-negative bacteria. Part of the type V secretion …