Immunity, tolerance and autoimmunity in the liver: A comprehensive review

DG Doherty - Journal of autoimmunity, 2016 - Elsevier
The hepatic immune system is constantly exposed to a massive load of harmless dietary and
commensal antigens, to which it must remain tolerant. Immune tolerance in the liver is …

Pathogenetic mechanisms of T cell dysfunction in chronic HBV infection and related therapeutic approaches

P Fisicaro, V Barili, M Rossi, I Montali, A Vecchi… - Frontiers in …, 2020 - frontiersin.org
A great effort of research has been devoted in the last few years to develo** new anti-HBV
therapies of finite duration that also provide effective sustained control of virus replication …

Protective Role of γδ T Cells in Different Pathogen Infections and Its Potential Clinical Application

Y Zhao, L Lin, Z **ao, M Li, X Wu, W Li… - Journal of …, 2018 - Wiley Online Library
γδ T cells, a subgroup of T cells based on the γδ TCR, when compared with conventional T
cells (αβ T cells), make up a very small proportion of T cells. However, its various subgroups …

How to train your dragon: harnessing gamma delta T cells antiviral functions and trained immunity in a pandemic era

J Caron, LA Ridgley, M Bodman-Smith - Frontiers in immunology, 2021 - frontiersin.org
The emergence of viruses with pandemic potential such as the SARS-CoV-2 coronavirus
causing COVID-19 poses a global health challenge. There is remarkable progress in …

Spatiotemporal orchestration of macrophage activation trajectories by Vγ4 T cells during skin wound healing

W Hu, X Zhang, Z Liu, J Yang, H Sheng, Z Liu, C Chen… - Iscience, 2024 - cell.com
Dysregulated macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2
phenotypes underlies impaired cutaneous wound healing. This study reveals Vγ4+ γδ T …

Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B

KM Chang, D Traum, JJ Park, S Ho, K Ojiro… - PLoS …, 2019 - journals.plos.org
Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-
cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection …

Classification and function of γδT cells and its research progress in anti-glioblastoma

Y Zhao, R Zhu, Y Wang, K Wang - Discover Oncology, 2023 - Springer
Human peripheral blood T lymphocytes are classified into alpha–beta T (αβΤ) cells and
gamma–delta T (γδΤ) cells based on the difference in T cell receptors (TCRs). αβT cells are …

Cytomegalovirus infection alters phenotypes of different γδ T‐cell subsets in renal transplant recipients with long‐term stable graft function

S Lee, JS Affandi, AB Irish… - Journal of Medical Virology, 2017 - Wiley Online Library
Cytomegalovirus (CMV) infection alters the phenotypic profiles of T‐cells and NK cells in
healthy and immunocompromised individuals. Here, we examined the effects of CMV …

Diverse functions of γδ T cells in the progression of hepatitis B virus and hepatitis C virus infection

W Hou, X Wu - Frontiers in Immunology, 2021 - frontiersin.org
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are primary risk factors for a
wide spectrum of liver diseases that severely affect human health. The liver is an …

[HTML][HTML] The Contribution of Human Herpes Viruses to γδ T Cell Mobilisation in Co-Infections

F Martini, E Champagne - Viruses, 2021 - mdpi.com
γδ T cells are activated in viral, bacterial and parasitic infections. Among viruses that
promote γδ T cell mobilisation in humans, herpes viruses (HHVs) occupy a particular place …