The hydration of biomolecules is one of the fundamental processes underlying the
construction of living matter. The formation of the native conformation of most biomolecules …

Water is more than an inert spectator during liquid–liquid phase separation (LLPS), the
reversible compartmentalization of protein solutions into a protein-rich and a dilute phase …

Water drives the spontaneous self-assembly of lipids and proteins into quasi two-
dimensional biological membranes that act as catalytic scaffolds for numerous processes …

Glycerol is a major cryoprotective agent and is widely used to promote protein stabilization.
By a combined experimental and theoretical study, we show that global thermodynamic …

Hydration free energies are dictated by a subtle balance of hydrophobic and hydrophilic
interactions. We present here a spectroscopic approach, which gives direct access to the …

Biological condensates are known to retain a large fraction of water to remain in a liquid and
reversible state. Local solvation contributions from water hydrating hydrophilic and …

Understanding how protein rich condensates formed upon liquid–liquid phase separation
(LLPS) evolve into solid aggregates is of fundamental importance for several medical …

Proteins and water couple dynamically over a wide range of time scales. Motivated by their
central role in protein function, protein-water dynamics and thermodynamics have been …

In nature and many technological applications, aqueous solutions are in contact with
patterned surfaces, which are dynamic over time scales spanning from ps to μs. For …

Fibrillar collagen accumulation emerges as a promising biomarker in several diseases, such
as desmoplastic tumors and unstable atherosclerotic plaque. Gold nanorods (GNRs) hold …