A survey of best practices for RNA-seq data analysis

A Conesa, P Madrigal, S Tarazona, D Gomez-Cabrero… - Genome biology, 2016 - Springer
Abstract RNA-sequencing (RNA-seq) has a wide variety of applications, but no single
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …

[HTML][HTML] Omics approaches for understanding heavy metal responses and tolerance in plants

M Jamla, T Khare, S Joshi, S Patil, S Penna… - Current Plant …, 2021 - Elsevier
Recent years have witnessed a gradual increase in the bioavailability and groundwater
leaching of toxic heavy metals (HMs) in the environment, driven mainly by anthropogenic …

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

DL Swaney, P Beltrao, L Starita, A Guo, J Rush… - Nature …, 2013 - nature.com
Cross-talk between different types of post-translational modifications on the same protein
molecule adds specificity and combinatorial logic to signal processing, but it has not been …

Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation

O Moiseeva, X Deschênes‐Simard, E St‐Germain… - Aging cell, 2013 - Wiley Online Library
We show that the antidiabetic drug metformin inhibits the expression of genes coding for
multiple inflammatory cytokines seen during cellular senescence. Conditioned medium (CM) …

[HTML][HTML] The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure

M Ruiz-Alonso, D Blesa, P Díaz-Gimeno, E Gómez… - Fertility and sterility, 2013 - Elsevier
Objective To demonstrate the clinical value of the endometrial receptivity array (ERA) in
patients with repeated implantation failure (RIF), for guiding their personalized embryo …

The human mitochondrial transcriptome

TR Mercer, S Neph, ME Dinger, J Crawford, MA Smith… - Cell, 2011 - cell.com
The human mitochondrial genome comprises a distinct genetic system transcribed as
precursor polycistronic transcripts that are subsequently cleaved to generate individual …

Genome-wide analysis of long noncoding RNA stability

MB Clark, RL Johnston, M Inostroza-Ponta… - Genome …, 2012 - genome.cshlp.org
Transcriptomic analyses have identified tens of thousands of intergenic, intronic, and cis-
antisense long noncoding RNAs (lncRNAs) that are expressed from mammalian genomes …

Hsa-miR-30d, secreted by the human endometrium, is taken up by the pre-implantation embryo and might modify its transcriptome

F Vilella, JM Moreno-Moya, N Balaguer… - …, 2015 - journals.biologists.com
During embryo implantation, the blastocyst interacts with and regulates the endometrium,
and endometrial fluid secreted by the endometrial epithelium nurtures the embryo. Here, we …

Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs

RE Green, EL Braun, J Armstrong, D Earl, N Nguyen… - Science, 2014 - science.org
INTRODUCTION Crocodilians and birds are the two extant clades of archosaurs, a group
that includes the extinct dinosaurs and pterosaurs. Fossils suggest that living crocodilians …

Next maSigPro: updating maSigPro bioconductor package for RNA-seq time series

MJ Nueda, S Tarazona, A Conesa - Bioinformatics, 2014 - academic.oup.com
Motivation: The widespread adoption of RNA-seq to quantitatively measure gene expression
has increased the scope of sequencing experimental designs to include time-course …