Background Epigenetic clocks can track both chronological age (cAge) and biological age
(bAge). The latter is typically defined by physiological biomarkers and risk of adverse health …

Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …

The aim of the present study was to provide a comprehensive characterization of whole
genome DNA methylation patterns in replicative and ionizing irradiation-or doxorubicin …

Abstract Background Intracranial aneurysms (IAs) pose a significant and intricate challenge.
Elucidating the interplay between DNA methylation and IA pathogenesis is paramount to …

DNA methylation (DNAm) has been reported to be associated with many diseases and with
mortality. We hypothesized that the integration of DNAm with clinical risk factors would …

Background Flaws in the science supporting pesticide risk assessment and regulation stand
in the way of progress in mitigating the human health impacts of pesticides. Critical problems …

DNA methylation commonly occurs at cytosine-phosphate-guanine sites (CpGs) that can
serve as biomarkers for many diseases. We analyzed whole genome sequencing data to …

Aims/hypothesis DNA methylation studies of incident type 2 diabetes in US populations are
limited and to our knowledge none include individuals of African descent. We aimed to fill …

Purpose The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that
has been reported to be associated with survival after chronic disease diagnoses, including …

Obesity is directly connected to lifestyle and has been associated with DNA methylation
changes that may cause alterations in the adipogenesis and lipid storage processes …