Cell motility is a crucial biological process that plays a critical role in the development of
multicellular organisms and is essential for tissue formation and regeneration. However …

Oblique plane microscopy (OPM) directly captures object information in a plane tilted from
the focal plane of the objective lens without the need for slow z-stack acquisition. This …

Structured illumination microscopy (SIM) doubles the spatial resolution of a fluorescence
microscope without requiring high laser powers or specialized fluorophores. However, the …

Due to the size and opacity of vertebrate brains, it has until now been impossible to
simultaneously record neuronal activity at cellular resolution across the entire adult brain. As …

Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric
imaging of cleared tissues. However, there is a need for a flexible system that can address …

Light sheet microscopy is a powerful technique for high-speed three-dimensional imaging of
subcellular dynamics and large biological specimens. However, it often generates datasets …

Elucidating the developmental processes of organisms requires a comprehensive
understanding of cellular lineages in the spatial, temporal, and molecular domains. In this …

In recent years, technological advances in tissue preparation, high‐throughput volumetric
microscopy, and computational infrastructure have enabled rapid developments in …

In this work, we describe a method for large-scale 3D cell-tracking through a segmentation
selection approach. The proposed method is effective at tracking cells across large …

Elucidating organismal developmental processes requires a comprehensive understanding
of cellular lineages in the spatial, temporal, and molecular domains. In this study, we …