Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Cloud computing for genomic data analysis and collaboration

B Langmead, A Nellore - Nature Reviews Genetics, 2018 - nature.com
Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …

Comprehensive analysis of DNA methylation data with RnBeads

Y Assenov, F Müller, P Lutsik, J Walter, T Lengauer… - Nature …, 2014 - nature.com
RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation
data, providing a user-friendly analysis workflow that yields detailed hypertext reports …

A survey of data-intensive scientific workflow management

J Liu, E Pacitti, P Valduriez, M Mattoso - Journal of Grid Computing, 2015 - Springer
Nowadays, more and more computer-based scientific experiments need to handle massive
amounts of data. Their data processing consists of multiple computational steps and …

The real cost of sequencing: higher than you think!

A Sboner, XJ Mu, D Greenbaum, RK Auerbach… - Genome biology, 2011 - Springer
The real cost of sequencing: higher than you think! | Genome Biology Skip to main content
SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart …

Next-generation sequencing data interpretation: enhancing reproducibility and accessibility

A Nekrutenko, J Taylor - Nature Reviews Genetics, 2012 - nature.com
Areas of life sciences research that were previously distant from each other in ideology,
analysis practices and toolkits, such as microbial ecology and personalized medicine, have …

NCBI BLAST+ integrated into Galaxy

PJA Cock, JM Chilton, B Grüning, JE Johnson… - …, 2015 - academic.oup.com
Abstract Background The NCBI BLAST suite has become ubiquitous in modern molecular
biology and is used for small tasks such as checking capillary sequencing results of single …

Managing, analysing, and integrating big data in medical bioinformatics: open problems and future perspectives

I Merelli, H Pérez-Sánchez, S Gesing… - BioMed research …, 2014 - Wiley Online Library
The explosion of the data both in the biomedical research and in the healthcare systems
demands urgent solutions. In particular, the research in omics sciences is moving from a …

[HTML][HTML] Practical computational reproducibility in the life sciences

B Grüning, J Chilton, J Köster, R Dale, N Soranzo… - Cell systems, 2018 - cell.com
Many areas of research suffer from poor reproducibility, particularly in computationally
intensive domains where results rely on a series of complex methodological decisions that …

CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computing

SV Angiuoli, M Matalka, A Gussman, K Galens… - BMC …, 2011 - Springer
Background Next-generation sequencing technologies have decentralized sequence
acquisition, increasing the demand for new bioinformatics tools that are easy to use …