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[HTML][HTML] Empowering biomedical discovery with AI agents
We envision" AI scientists" as systems capable of skeptical learning and reasoning that
empower biomedical research through collaborative agents that integrate AI models and …
empower biomedical research through collaborative agents that integrate AI models and …
Optimizing the Cell Painting assay for image-based profiling
In image-based profiling, software extracts thousands of morphological features of cells from
multi-channel fluorescence microscopy images, yielding single-cell profiles that can be used …
multi-channel fluorescence microscopy images, yielding single-cell profiles that can be used …
Masked autoencoders for microscopy are scalable learners of cellular biology
Featurizing microscopy images for use in biological research remains a significant
challenge especially for large-scale experiments spanning millions of images. This work …
challenge especially for large-scale experiments spanning millions of images. This work …
[HTML][HTML] How to build the virtual cell with artificial intelligence: Priorities and opportunities
Cells are essential to understanding health and disease, yet traditional models fall short of
modeling and simulating their function and behavior. Advances in AI and omics offer …
modeling and simulating their function and behavior. Advances in AI and omics offer …
Learning representations for image-based profiling of perturbations
Measuring the phenotypic effect of treatments on cells through imaging assays is an efficient
and powerful way of studying cell biology, and requires computational methods for …
and powerful way of studying cell biology, and requires computational methods for …
Evaluating batch correction methods for image-based cell profiling
High-throughput image-based profiling platforms are powerful technologies capable of
collecting data from billions of cells exposed to thousands of perturbations in a time-and cost …
collecting data from billions of cells exposed to thousands of perturbations in a time-and cost …
Deep learning in image-based phenotypic drug discovery
Modern drug discovery approaches often use high-content imaging to systematically study
the effect on cells of large libraries of chemical compounds. By automatically screening …
the effect on cells of large libraries of chemical compounds. By automatically screening …
JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
Image-based profiling has emerged as a powerful technology for various steps in basic
biological and pharmaceutical discovery, but the community has lacked a large, public …
biological and pharmaceutical discovery, but the community has lacked a large, public …
[HTML][HTML] CLOOME: contrastive learning unlocks bioimaging databases for queries with chemical structures
The field of bioimage analysis is currently impacted by a profound transformation, driven by
the advancements in imaging technologies and artificial intelligence. The emergence of …
the advancements in imaging technologies and artificial intelligence. The emergence of …
Cell Painting: a decade of discovery and innovation in cellular imaging
Modern quantitative image analysis techniques have enabled high-throughput, high-content
imaging experiments. Image-based profiling leverages the rich information in images to …
imaging experiments. Image-based profiling leverages the rich information in images to …