Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete
description of specific immune biomarkers. We present here a comprehensive multi-omic …

Although the subcellular dynamics of RNA and proteins are key determinants of cell
homeostasis, their characterization is still challenging. Here we present an integrative …

Mucosal-associated invariant T (MAIT) cells are innate sensors of viruses and can augment
early immune responses and contribute to protection. We hypothesized that MAIT cells may …

Here we describe single-cell corrected long-read sequencing (scCOLOR-seq), which
enables error correction of barcode and unique molecular identifier oligonucleotide …

Unique molecular identifiers are random oligonucleotide sequences that remove PCR
amplification biases. However, the impact that PCR associated sequencing errors have on …

Increased interleukin (IL)-17A has been identified in joints affected by osteoarthritis (OA), but
it is unclear how IL-17A, and its family members IL-17AF and IL-17F, can contribute to …

For more than 20 years, robotic bioreactor systems have facilitated the growth of tissue-
engineered constructs using mechanical stimulation. However, we are still unable to …

T helper (Th) cells are CD4+ effector T cells that play a critical role in immunity by sha**
the inflammatory cytokine environment in a variety of physiological and pathological …

Context. Hickson compact groups (HCGs) are dense configurations of four to ten galaxies,
whose HI morphology appears to follow an evolutionary sequence of three phases, with gas …

Single-cell multiomic analysis of the epigenome, transcriptome, and proteome allows for
comprehensive characterization of the molecular circuitry that underpins cell identity and …