Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

A Currin, N Swainston, PJ Day, DB Kell - Chemical Society Reviews, 2015 - pubs.rsc.org
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

A review of long‐branch attraction

J Bergsten - Cladistics, 2005 - Wiley Online Library
The history of long‐branch attraction, and in particular methods suggested to detect and
avoid the artifact to date, is reviewed. Methods suggested to avoid LBA‐artifacts include …

[CARTE][B] Modern phylogenetic comparative methods and their application in evolutionary biology: concepts and practice

LZ Garamszegi - 2014 - Springer
Many evolutionary biologists are concerned with the tremendous amount of diversity of
species, and their phenotypes, that we can currently observe in nature, and one of the most …

A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood

S Guindon, O Gascuel - Systematic biology, 2003 - academic.oup.com
The increase in the number of large data sets and the complexity of current probabilistic
sequence evolution models necessitates fast and reliable phylogeny reconstruction …

[CARTE][B] Molecular evolution and phylogenetics

M Nei, S Kumar - 2000 - books.google.com
During the last ten years, remarkable progress has occurred in the study of molecular
evolution. Among the most important factors that are responsible for this progress are the …

[CARTE][B] Phylogeography: the history and formation of species

JC Avise - 2000 - books.google.com
Phylogeography is a discipline concerned with various relationships between gene
genealogies—phylogenetics—and geography. The word “phylogeography” was coined in …

DNA barcoding and taxonomy in Diptera: a tale of high intraspecific variability and low identification success

R Meier, K Shiyang, G Vaidya, PKL Ng - Systematic biology, 2006 - academic.oup.com
DNA barcoding and DNA taxonomy have recently been proposed as solutions to the crisis of
taxonomy and received significant attention from scientific journals, grant agencies, natural …

MEGA2: molecular evolutionary genetics analysis software

S Kumar, K Tamura, IB Jakobsen, M Nei - Bioinformatics, 2001 - academic.oup.com
We have developed a new software package, Molecular Evolutionary Genetics Analysis
version 2 (MEGA2), for exploring and analyzing aligned DNA or protein sequences from an …

Combination antifungal therapy for cryptococcal meningitis

JN Day, TTH Chau, M Wolbers, PP Mai… - … England Journal of …, 2013 - Mass Medical Soc
Background Combination antifungal therapy (amphotericin B deoxycholate and flucytosine)
is the recommended treatment for cryptococcal meningitis but has not been shown to reduce …

[CARTE][B] Evolution: Probleme—Themen—Fragen

M Ridley - 2013 - books.google.com
Beim Studium der jüngeren Kontroversen über den Darwinismus fiel mir wiederholt auf, das
sie falsche Darstellungen enthielten, so als würde es sich um irgendetwas Umfassenderes …