Enhancement of ketoprofen dissolution rate by the liquisolid technique: Optimization and in vitro and in vivo investigations
The objective of the current study is to evaluate the prospective of liquisolid formulation to
improve the dissolution rate of ketoprofen and thereby the bioavailability. Different batches …
improve the dissolution rate of ketoprofen and thereby the bioavailability. Different batches …
Ketoprofen–FA Co-crystal: In Vitro and In Vivo Investigation for the Solubility Enhancement of Drug by Design of Expert
The present piece of research work is framed for improving the solubility of ketoprofen by
forming co-crystal using fumaric acid as a coformer. Co-crystal of ketoprofen and fumaric …
forming co-crystal using fumaric acid as a coformer. Co-crystal of ketoprofen and fumaric …
Improved solubility and dissolution rate of ketoprofen by the formation of multicomponent crystals with tromethamine
This study aims to improve the dissolution rate of ketoprofen by preparing multicomponent
crystals with tromethamine. The multicomponent crystals (equimolar ratio) of ketoprofen and …
crystals with tromethamine. The multicomponent crystals (equimolar ratio) of ketoprofen and …
Co-crystallization: a green approach for the solubility enhancement of poorly soluble drugs
M Bhatia, S Devi - CrystEngComm, 2024 - pubs.rsc.org
Recently, the co-crystallization of pharmaceutical drugs is gaining consideration because it
is an environmentally friendly and potentially effective technique to improve the solubility …
is an environmentally friendly and potentially effective technique to improve the solubility …
Development of ketoprofen-p-aminobenzoic acid co-crystal: formulation, characterization, optimization, and evaluation
In the present study, ketoprofen-p-aminobenzoic acid (KP-PABA) co-crystal was prepared, to
advance solubility and dissolution rate of drug, by solvent evaporation technique employing …
advance solubility and dissolution rate of drug, by solvent evaporation technique employing …
Enhancing Ketoprofen Solubility: A Strategic Approach Using Solid Dispersion and Response Surface Methodology
Background In the pharmaceutical sciences, the solubility profile of therapeutic molecules is
crucial for identifying and formulating drugs and evaluating their quality across the drug …
crucial for identifying and formulating drugs and evaluating their quality across the drug …
Solid Dispersion Formulation Methods and Applications in Drug Delivery
N Sihag, K Bahmani, S Grewal, R Tanwar… - Current Physical …, 2024 - benthamdirect.com
About 44% of the active medicinal components in all previously disclosed chemical units are
hydrophobic and do not extend shop because of their limited water solubility. One of the …
hydrophobic and do not extend shop because of their limited water solubility. One of the …
Development of hesperidin solid dispersion for improved solubility and dissolution using mannitol and PVP K30 as carriers
P Swarup, GP Agrawal - Journal of Applied Pharmaceutical …, 2024 - japtronline.com
Background: Despite its six-hour half-life, Hesperidin, a bioflavonoid with therapeutic
benefits, has low water solubility and bioavailability. This limits treatment. This study …
benefits, has low water solubility and bioavailability. This limits treatment. This study …
[PDF][PDF] A study on solubility enhancement of etravirine by crystal engineering method
S Bhattacharyya, H Adhikari, D Regmi… - Indian J Pharm …, 2022 - academia.edu
Etravirine, an antiretroviral agent, used in the treatment of human immunodeficiency virus
belongs to biopharmaceutical classification system classification IV. The reported solubility …
belongs to biopharmaceutical classification system classification IV. The reported solubility …
Formulation and optimization: Liquisolid of domperidone for solubility enhancement
M BHATIA, R Geeta, K BAHMANI… - ACTA Pharmaceutica … - actapharmsci.com
In the present study, liquisolid formulations of domperidone were prepared using Tween 80,
microcrystalline cellulose, Aerosil 200 as solvent, carrier, and coating material, respectively …
microcrystalline cellulose, Aerosil 200 as solvent, carrier, and coating material, respectively …