Applications of clustering algorithms in biomedical research are ubiquitous, with typical
examples including gene expression data analysis, genomic sequence analysis, biomedical …

Expressed sequence tag (EST) sequencing projects are underway for numerous organisms,
generating millions of short, single-pass nucleotide sequence reads, accumulating in EST …

This is the first book to take a truly comprehensive look at clustering. It begins with an
introduction to cluster analysis and goes on to explore: proximity measures; hierarchical …

Genomic comparisons provide evidence for ancient genome-wide duplications in a diverse
array of animals and plants. We developed a birth–death model to identify evidence for …

Genomics and bioinformatics have great potential to help address numerous topics in
ecology and evolution. Expressed sequence tags (ESTs) can bridge genomics and …

Background We have developed a simulation approach to help determine the optimal
mixture of sequencing methods for most complete and cost effective transcriptome …

Whereas de novo assemblies of RNA-Seq data are being published for a growing number of
species across the tree of life, there are currently no broadly accepted methods for …

Background Bed bugs (Cimex lectularius) are blood-feeding insects poised to become one
of the major pests in households throughout the United States. Resistance of C. lectularius …

Background Giant freshwater prawn (Macrobrachium rosenbergii or GFP), is the most
economically important freshwater crustacean species. However, as little is known about its …

Background Turbot (Scophthalmus maximus L.) is an important aquacultural resource both
in Europe and Asia. However, there is little information on gene sequences available in …