NAFLD: mechanisms, treatments, and biomarkers

F Nassir - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …

Diagnosis and management of cirrhosis and its complications: a review

EB Tapper, ND Parikh - Jama, 2023 - jamanetwork.com
Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021,
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Using the ELF test, FIB-4 and NAFLD fibrosis score to screen the population for liver disease

M Kjaergaard, KP Lindvig, KH Thorhauge… - Journal of …, 2023 - Elsevier
Background & Aims There is a need for accurate biomarkers of fibrosis for population
screening of alcohol-related and non-alcoholic fatty liver disease (ALD, NAFLD). We …

Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study

M Serra-Burriel, A Juanola, F Serra-Burriel, M Thiele… - The Lancet, 2023 - thelancet.com
Background Liver cirrhosis is a major cause of death worldwide. Cirrhosis develops after a
long asymptomatic period of fibrosis progression, with the diagnosis frequently occurring …

Liver biopsy-based validation, confirmation and comparison of the diagnostic performance of established and novel non-invasive steatotic liver disease indexes …

M Kouvari, L Valenzuela-Vallejo, V Guatibonza-Garcia… - Metabolism, 2023 - Elsevier
Background Non-invasive tools (NIT) for metabolic-dysfunction associated liver disease
(MASLD) screening or diagnosis need to be thoroughly validated using liver biopsies …

Steatotic liver disease

M Israelsen, S Francque, EA Tsochatzis, A Krag - The Lancet, 2024 - thelancet.com
Steatotic liver disease is the overarching term for conditions characterised by abnormal lipid
accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses …

Waiting for the changes after the adoption of steatotic liver disease

EL Yoon, DW Jun - Clinical and Molecular Hepatology, 2023 - pmc.ncbi.nlm.nih.gov
Steatotic liver disease was suggested as an overarching term encompassing various
etiologies of hepatic steatosis. Experts from multinational liver societies went through the …

Precision medicine in fatty liver disease/non-alcoholic fatty liver disease

L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

Nonalcoholic fatty liver disease and staging of hepatic fibrosis

A Engin - Obesity and Lipotoxicity, 2024 - Springer
Nonalcoholic fatty liver disease (NAFLD) is in parallel with the obesity epidemic, and it is the
most common cause of liver diseases. The patients with severe insulin-resistant diabetes …