Stem cells for cartilage repair: preclinical studies and insights in translational animal models and outcome measures

M Lo Monaco, G Merckx, J Ratajczak… - Stem Cells …, 2018 - Wiley Online Library
Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …

Use of computational modeling to study joint degeneration: a review

S Mukherjee, M Nazemi, I Jonkers… - … in Bioengineering and …, 2020 - frontiersin.org
Osteoarthritis (OA), a degenerative joint disease, is the most common chronic condition of
the joints, which cannot be prevented effectively. Computational modeling of joint …

CT-and MRI-based 3D reconstruction of knee joint to assess cartilage and bone

FK Ciliberti, L Guerrini, AE Gunnarsson, M Recenti… - Diagnostics, 2022 - mdpi.com
For the observation of human joint cartilage, X-ray, computed tomography (CT) or magnetic
resonance imaging (MRI) are the main diagnostic tools to evaluate pathologies or traumas …

PET/MRI of metabolic activity in osteoarthritis: a feasibility study

F Kogan, AP Fan, EJ McWalter, EHG Oei… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose To evaluate positron emission tomography/magnetic resonance imaging (PET/MRI)
knee imaging to detect and characterize osseous metabolic abnormalities and correlate PET …

Osteoarthritis of the temporomandibular joint: a narrative overview

C Mélou, P Pellen-Mussi, S Jeanne, A Novella… - Medicina, 2022 - mdpi.com
Background and Objectives: This study reviewed the literature to summarize the current and
recent knowledge of temporomandibular joint osteoarthritis (TMJOA). Methods: Through a …

Quantitative imaging of excised osteoarthritic cartilage using spectral CT

K Rajendran, C Löbker, BS Schon, CJ Bateman… - European …, 2017 - Springer
Objectives To quantify iodine uptake in articular cartilage as a marker of glycosaminoglycan
(GAG) content using multi-energy spectral CT. Methods We incubated a 25-mm strip of …

Applications of PET‐MRI in musculoskeletal disease

F Kogan, SM Broski, D Yoon… - Journal of Magnetic …, 2018 - Wiley Online Library
New integrated PET‐MRI systems potentially provide a complete imaging modality for
diagnosis and evaluation of musculoskeletal disease. MRI is able to provide excellent high …

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

BB Nelson, CE Kawcak, MF Barrett… - Equine veterinary …, 2018 - Wiley Online Library
Articular cartilage is a critical joint tissue and its evaluation remains a diagnostic challenge
in horses. Coupled with a poor capacity for healing, early degenerative changes in articular …

Assessing cartilage biomechanical properties: techniques for evaluating the functional performance of cartilage in health and disease

BA Lakin, BD Snyder… - Annual review of …, 2017 - annualreviews.org
Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due
to overloading. During joint articulation, hyaline cartilage must withstand high loads while …

Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: A feasibility study

DB Abrar, C Schleich, KL Radke, M Frenken… - … Resonance Materials in …, 2021 - Springer
Objective To establish and optimize a stable 3 Tesla (T) glycosaminoglycan chemical
exchange saturation transfer (gagCEST) imaging protocol for assessing the articular …