Malaria is a devastating infectious disease and significant global health burden caused by
the bite of a Plasmodium-infected female Anopheles mosquito. Gut microbiota was recently …

Malaria remains a relevant global health problem. In 2021, the WHO estimated 247 million
cases worldwide, which led to more than 600,000 deaths, mainly due to severe malaria …

Malaria-causing Plasmodium parasites first replicate as liver stages (LS), which then seed
symptomatic blood stage (BS) infection. Emerging evidence suggests that these stages …

Abstract γδ T cells producing either interleukin-17A (γδ17 cells) or interferon-γ (γδIFN cells)
are generated in the mouse thymus, but the molecular regulators of their peripheral …

Malaria is still a major endemic disease transmitted in humans via Plasmodium-infected
mosquitoes. The eradication of malarial parasites and the control measures have been …

The neuroimmune axis has been the focus of many studies, with special emphasis on the
interactions between the central nervous system and the different immune cell subsets. T …

Abstract γδ T cells play diverse roles in immune responses, producing either interleukin (IL)-
17A or interferon γ (IFN-γ). Here, we investigated the impact of this functional dichotomy on …

Chora and colleagues show that infection of the liver by Plasmodium modulates severity of
disease in the experimental cerebral malaria (ECM) model by generating gamma delta (ɣδ) …

Dendritic cells (DC) are pivotal for initiating adaptive immunity, a process triggered by the
activation of DC via pathogen products or damage. Here, we describe an additional layer to …

A signature remains elusive of naturally-acquired immunity against Plasmodium falciparum.
We identified P. falciparum in a 14-month cohort of 239 people in Kenya, genotyped at …