Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

Phosphocreatine (PCr) plays a vital role in neuron and myocyte energy homeostasis.
Currently, there are no routine diagnostic tests to noninvasively map PCr distribution with …

In addition to direct assessment of high energy phosphorus containing metabolite content
within tissues, phosphorus magnetic resonance spectroscopy (31 P-MRS) provides options …

Many human diseases are caused by an imbalance between energy production and
demand. Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) …

In vivo magnetic resonance spectroscopy provides insight into metabolism in the human
body. New acquisition protocols are often proposed to improve the quality or efficiency of …

Introduction Deuterium metabolic imaging (DMI) and quantitative exchange label turnover
(QELT) are novel MR spectroscopy techniques for non-invasive imaging of human brain …

Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …

Magnetic resonance signals from different nuclei can be excited or received at the same
time, rendering simultaneous or rapidly interleaved multi‐nuclear acquisitions feasible. The …

Purpose In vivo 31P MRSI enables noninvasive map** of absolute pH values via the pH‐
dependent chemical shifts of inorganic phosphates (Pi). A particular challenge is the …