What does immunology have to do with normal brain development and the pathophysiology underlying Tourette syndrome and related neuropsychiatric disorders?

D Martino, I Johnson, JF Leckman - Frontiers in Neurology, 2020 - frontiersin.org
Objective: The goal of this article is to review the past decade's literature and provide a
critical commentary on the involvement of immunological mechanisms in normal brain …

[HTML][HTML] Effect of short-term deep-pressure portable seat on behavioral and biological stress in children with autism spectrum disorders: A pilot study

IY Afif, M Farkhan, O Kurdi, MI Maula, MI Ammarullah… - Bioengineering, 2022 - mdpi.com
Children with autism spectrum disorder (ASD) have challenging behaviors, which are
associated with difficulties in parenting. Deep pressure is a therapeutic modality in …

Maternal immune conditions are increased in males with autism spectrum disorders and are associated with behavioural and emotional but not cognitive co-morbidity

S Patel, RC Dale, D Rose, B Heath, CW Nordahl… - Translational …, 2020 - nature.com
Epidemiological and animal research shows that maternal immune activation increases the
risk of autism spectrum disorders (ASD) in offspring. Emerging evidence suggests that …

[HTML][HTML] Dissecting molecular genetic mechanisms of 1q21. 1 CNV in neuropsychiatric disorders

J Yoon, Y Mao - International journal of molecular sciences, 2021 - mdpi.com
Pathogenic copy number variations (CNVs) contribute to the etiology of
neurodevelopmental/neuropsychiatric disorders (NDs). Increased CNV burden has been …

Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing

R Trifiletti, HM Lachman, O Manusama, D Zheng… - Scientific reports, 2022 - nature.com
Abrupt onset of severe neuropsychiatric symptoms including obsessive–compulsive
disorder, tics, anxiety, mood swings, irritability, and restricted eating is described in children …

[HTML][HTML] Prenatal and early childhood infections and subsequent risk of obsessive-compulsive disorder and tic disorders: a nationwide, sibling-controlled study

T Zhang, G Brander, J Isung, K Isomura, A Sidorchuk… - Biological …, 2023 - Elsevier
Background Postinfectious autoimmune processes are hypothesized to be causally related
to both obsessive-compulsive disorder (OCD) and tic disorders, but current evidence is …

Maternal immune-related conditions during pregnancy may be a risk factor for neuropsychiatric problems in offspring throughout childhood and adolescence

S Patel, MN Cooper, H Jones… - Psychological …, 2021 - cambridge.org
BackgroundEmerging research suggests that maternal immune activation (MIA) may be
associated with an increased risk of adverse neurodevelopmental and mental health …

Could the thyroid gland dominate the brain in obsessive-compulsive disorder?

A Caykoylu, E Kabadayi Sahin, M Ugurlu - Neuroendocrinology, 2022 - karger.com
Thyroid hormones have an essential role in brain maturation and neuronal functioning. The
comorbidity of thyroid disorders and several mental disturbances is frequently reported. We …

Evaluation of thyroid function tests among children with neurological disorders

H Meng, FM Bigambo, W Gu, X Wang… - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Thyroid hormones (THs) are essential for brain development. Numerous
studies have identified significant links between thyroid dysfunction and cognitive function …

Increased prevalence of familial autoimmune disease in children with opsoclonus-myoclonus syndrome

JD Santoro, LM Kerr, R Codden, TC Casper… - Neurology …, 2021 - neurology.org
Background and Objectives Opsoclonus-myoclonus syndrome (OMS) is a rare autoimmune
disorder associated with neuroblastoma in children, although idiopathic and postinfectious …