Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

S Singh, N Pathak, E Fatima, AS Negi - European Journal of Medicinal …, 2021 - Elsevier
Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

Biologically active isoquinoline alkaloids covering 2014–2018

XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

E Plazas, DR Muñoz - Pharmacological Research, 2022 - Elsevier
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

Recent progress towards gold-catalyzed synthesis of N-containing tricyclic compounds based on ynamides

F Pan, C Shu, LW Ye - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
N-Containing tricyclic compounds, especially the tricyclic N-heterocycles, are important
structural motifs that possess significant potential in organic chemistry for their momentous …

Plant-derived alkaloids: the promising disease-modifying agents for inflammatory bowel disease

J Peng, TT Zheng, X Li, Y Liang, LJ Wang… - Frontiers in …, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) represents a group of intestinal disorders with self-
destructive and chronic inflammation in the digestive tract, requiring long-term medications …

Harnessing the chemical composition and anti-oxidant, anti-enzymatic, and anti-cancer activities of two Corydalis species (C. erdelii and C. solida) by using in vitro …

T Duran, G Peron, M Zancato, G Zengin, MV Cetiz… - Food Bioscience, 2024 - Elsevier
In search of a powerful source of bioactive molecules that can be imperative in maintaining
health, this paper studies two Corydalis species from the territory of Turkey. Namely, C …

Rh-Catalyzed Enantioselective Desymmetric Hydrogenation of α-Acetamido-1, 3-indanediones Using Ether-Bridged Biphenyl Diphosphine Ligands

Y Xu, Y Luo, J Ye, D Liu, W Zhang - Journal of the American …, 2023 - ACS Publications
Novel axially chiral biphenyl diphosphine ligands E nm-BridgePhos, bearing an ether chain
bridge at the 5, 5′-position of the biphenyl backbone, have been developed and …

Haber-independent, diversity-oriented synthesis of nitrogen compounds from biorenewable chitin

TT Pham, X Chen, T Söhnel, N Yan, J Sperry - Green Chemistry, 2020 - pubs.rsc.org
During drug discovery programmes, medicinal chemists rely on compounds derived from
Haber ammonia as the source of this clinically important nitrogen heteroatom and as a …

Metal-free intermolecular formal cycloadditions enable an orthogonal access to nitrogen heterocycles

LG **e, S Niyomchon, AJ Mota, L González… - Nature …, 2016 - nature.com
Nitrogen-containing heteroaromatic cores are ubiquitous building blocks in organic
chemistry. Herein, we present a family of metal-free intermolecular formal cycloaddition …

Isoquinoline alkaloids and their antiviral, antibacterial, and antifungal activities and structure-activity relationship

ZX Qing, P Yang, Q Tang, P Cheng… - Current Organic …, 2017 - ingentaconnect.com
Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …