Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases

JA Hamilton, AD Cook, PP Tak - Nature reviews Drug discovery, 2017 - nature.com
Granulocyte–macrophage colony-stimulating factor (GM-CSF), macrophage colony-
stimulating factor (M-CSF; also known as CSF1), granulocyte colony-stimulating factor (G …

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

L Shen, PM Thompson, SG Potkin, L Bertram… - Brain imaging and …, 2014 - Springer
Abstract The Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI),
formally established in 2009, aims to provide resources and facilitate research related to …

IL-3 in the development and function of basophils

G Varricchi, R Poto, G Marone, JT Schroeder - Seminars in immunology, 2021 - Elsevier
The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

JF Brinkworth, LB Barreiro - Current opinion in immunology, 2014 - Elsevier
Highlights•GWAS suggest pathological inflammation is controlled by a small network of
genes.•Many chronic inflammatory/autoimmune risk alleles occur in regions of positive …

The βc receptor family–Structural insights and their functional implications

SE Broughton, TL Nero, U Dhagat, WL Kan, TR Hercus… - Cytokine, 2015 - Elsevier
Granulocyte–macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5
are members of a small family of cytokines that share a beta receptor subunit (βc). These …

Transcriptome of rhesus macaque (Macaca mulatta) exposed to total-body irradiation

Y Li, J Singh, R Varghese, Y Zhang, OO Fatanmi… - Scientific reports, 2021 - nature.com
The field of biodosimetry has seen a paradigm shift towards an increased use of molecular
phenoty** technologies including omics and miRNA, in addition to conventional …

[KNIHA][B] Music, evolution, and the harmony of souls

AR Harvey - 2017 - books.google.com
Music is central to human cultural and intellectual experience. It is vitally important for the
welfare of human society and-this book argues-should become more widely accepted in our …

Neuronal release of cytokine IL-3 triggered by mechanosensitive autostimulation of the P2X7 receptor is neuroprotective

JC Lim, W Lu, JM Beckel, CH Mitchell - Frontiers in cellular …, 2016 - frontiersin.org
Mechanical strain due to increased pressure or swelling activates inflammatory responses in
many neural systems. As cytokines and chemokine messengers lead to both pro …

IL-3 receptor expression on activated human Th cells is regulated by IL-4, and IL-3 synergizes with IL-4 to enhance Th2 cell differentiation

A Kumar, L Rani, ST Mhaske, ST Pote… - The Journal of …, 2020 - journals.aai.org
IL-3, a cytokine secreted by activated T lymphocytes, is known to regulate the proliferation,
survival, and differentiation of hematopoietic cells. However, the role of IL-3 in regulation of T …

GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea

X Luo, M Deng, X **e, L Huang, H Wang… - Human molecular …, 2013 - academic.oup.com
HDR syndrome (also known as Barakat syndrome) is a developmental disorder
characterized by hypoparathyroidism, sensorineural deafness and renal disease. Although …