Origins of specificity in protein-DNA recognition

R Rohs, X **, SM West, R Joshi… - Annual review of …, 2010 - annualreviews.org
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

[5] DNA structure from A to Z

RE Dickerson - Methods in Enzymology, 1992 - Elsevier
Publisher Summary This chapter shows sixteen-base-pair lengths of A-, B-, and Z-DNA on a
uniform scale, as a comparison and an illustration of their distinguishing features. Mean …

The role of DNA shape in protein–DNA recognition

R Rohs, SM West, A Sosinsky, P Liu, RS Mann… - Nature, 2009 - nature.com
The recognition of specific DNA sequences by proteins is thought to depend on two types of
mechanism: one that involves the formation of hydrogen bonds with specific bases, primarily …

Solution structure of the human telomeric repeat d [AG3 (T2AG3) 3] G-tetraplex

Y Wang, DJ Patel - Structure, 1993 - cell.com
Background: Repeats of O n sequences are detected as single strand overhangs at the ends
of eukaryotic chromosomes together with associated binding proteins. Such telomere …

3DNA: a software package for the analysis, rebuilding and visualization of three‐dimensional nucleic acid structures

XJ Lu, WK Olson - Nucleic acids research, 2003 - academic.oup.com
We present a comprehensive software package, 3DNA, for the analysis, reconstruction and
visualization of three‐dimensional nucleic acid structures. Starting from a coordinate file in …

[HTML][HTML] Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins

M Slattery, T Riley, P Liu, N Abe, P Gomez-Alcala… - Cell, 2011 - cell.com
Members of transcription factor families typically have similar DNA binding specificities yet
execute unique functions in vivo. Transcription factors often bind DNA as multiprotein …

Conformational analysis of nucleic acids revisited: Curves+

R Lavery, M Moakher, JH Maddocks… - Nucleic acids …, 2009 - academic.oup.com
We describe Curves+, a new nucleic acid conformational analysis program which is
applicable to a wide range of nucleic acid structures, including those with up to four strands …

Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape

R Gordân, N Shen, I Dror, T Zhou, J Horton, R Rohs… - Cell reports, 2013 - cell.com
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs)
for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with …

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

XJ Lu, WK Olson - Nature protocols, 2008 - nature.com
We present a set of protocols showing how to use the 3DNA suite of programs to analyze,
rebuild and visualize three-dimensional nucleic-acid structures. The software determines a …

Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn

PA Rice, S Yang, K Mizuuchi, HA Nash - Cell, 1996 - cell.com
Integration host factor (IHF) is a small heterodimeric protein that specifically binds to DNA
and functions as an architectural factor in many cellular processes in prokaryotes. Here, we …