Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
Flavonoids as potential anti-inflammatory molecules: A review
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …
The role of IL-6 in cancer cell invasiveness and metastasis—overview and therapeutic opportunities
M Rašková, L Lacina, Z Kejík, A Venhauerová… - Cells, 2022 - mdpi.com
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various
homeostatic and pathological processes. These activities range from regulating embryonic …
homeostatic and pathological processes. These activities range from regulating embryonic …
Antioxidants in brain tumors: current therapeutic significance and future prospects
Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …
microenvironment and inherent characteristics of brain tumor cells virtually render them …
Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer
management is associated with challenges considering risk assessment and predictive …
management is associated with challenges considering risk assessment and predictive …
Transient mild photothermia improves therapeutic performance of oral nanomedicines with enhanced accumulation in the colitis mucosa
The treatment outcomes of oral medications against ulcerative colitis (UC) have long been
restricted by low drug accumulation in the colitis mucosa and subsequent unsatisfactory …
restricted by low drug accumulation in the colitis mucosa and subsequent unsatisfactory …
[HTML][HTML] Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells–a potential contribution to the predictive, preventive …
A Mazurakova, L Koklesova, SH Csizmár… - Journal of Advanced …, 2024 - Elsevier
Background Cancer management faces multiple obstacles, including resistance to current
therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt …
therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt …
Cancer metabolism as a therapeutic target and review of interventions
Cancer is amenable to low-cost treatments, given that it has a significant metabolic
component, which can be affected through diet and lifestyle change at minimal cost. The …
component, which can be affected through diet and lifestyle change at minimal cost. The …
Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling
Cancer cell plasticity plays a crucial role in tumor initiation, progression, and metastasis and
is implicated in the multiple cancer defense mechanisms associated with therapy resistance …
is implicated in the multiple cancer defense mechanisms associated with therapy resistance …
unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities—preliminary data for PPPM validation
M Kropp, E De Clerck, TTKS Vo, G Thumann… - EPMA Journal, 2023 - Springer
Abstract Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-
dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global …
dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global …