The visual system is beautifully crafted to transmit information of the external world to visual
processing and cognitive centers in the brain. For visual information to be relayed to the …

This article reviews symptoms and signs of aberrant axon connectivity in humans, and
summarizes major human genetic disorders that result, or have been proposed to result …

To understand the mechanisms of cell fate determination in the vertebrate retina, the time
course of the generation of the major cell types needs to be established. This will help define …

" Due to the generous representation of the afferent visual system within the brain,
neurological disease may disrupt vision as a presenting symptom or as a secondary effect of …

In animals with binocular vision, retinal ganglion cell (RGC) axons either cross or avoid the
midline at the optic chiasm. Here, we show that ephrin-Bs in the chiasm region direct the …

The retinal pigment epithelium (RPE) plays an essential role in the normal development of
the underlying neural retina, but the mechanisms by which this regulation occurs are largely …

During CNS development, combinatorial expression of transcription factors controls
neuronal subtype identity and subsequent axonal trajectory. Regulatory genes designating …

Retinal ganglion cells (RGCs) are the projection neurons of the retina and transmit visual
information to postsynaptic targets in the brain. While this function is shared among nearly …

Based on the procedure of Prusky et al.(2000, Vision Research, 40, 2201–2209), we used a
computer‐based, two‐alternative swim task to evaluate visual detection, pattern …

At the optic chiasm, retinal ganglion cell axons from each eye converge and segregate into
crossed and uncrossed projections, a pattern critical for binocular vision. Here, we review …