Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

The emergence of new sequencing technologies has facilitated the use of bacterial whole
genome alignments for evolutionary studies and outbreak analyses. These datasets, of …

Streptococcus pneumoniae is a major pathogen of humans, causing diseases such as
pneumonia and meningitis. The organism produces several virulence factors that are …

Background Streptococcus pneumoniae is one of the most important causes of microbial
diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed …

Streptococcus agalactiae (group B Streptococcus) is the major cause of invasive bacterial
disease, including meningitis, in the neonatal period. Although prophylactic measures have …

Streptococcus pneumoniae is a common cause of pneumonia and infective exacerbations of
chronic lung disease, yet there are few data on how adaptive immunity can specifically …

Streptococcus pneumoniae serotype 3 remains a significant cause of morbidity and mortality
worldwide, despite inclusion in the 13-valent pneumococcal conjugate vaccine (PCV13) …

Pneumococcal infections continue to pose a significant global health concern, necessitating
the development of effective vaccines. Despite the progress shown by pneumococcal …

Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-
threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic …