Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Poly (vinyl alcohol) hydrogels with broad‐range tunable mechanical properties via the Hofmeister effect

S Wu, M Hua, Y Alsaid, Y Du, Y Ma, Y Zhao… - Advanced …, 2021 - Wiley Online Library
Hydrogels, exhibiting wide applications in soft robotics, tissue engineering, implantable
electronics, etc., often require sophisticately tailoring of the hydrogel mechanical properties …

Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels

WJ Hadden, JL Young, AW Holle… - Proceedings of the …, 2017 - National Acad Sciences
The spatial presentation of mechanical information is a key parameter for cell behavior. We
have developed a method of polymerization control in which the differential diffusion …

Rational design of network properties in guest–host assembled and shear-thinning hyaluronic acid hydrogels

CB Rodell, AL Kaminski, JA Burdick - Biomacromolecules, 2013 - ACS Publications
Shear-thinning hydrogels afford direct injection or catheter delivery to tissues without
potential premature gel formation and delivery failure or the use of triggers such as chemical …

Tuning chemistry and topography of nanoengineered surfaces to manipulate immune response for bone regeneration applications

Z Chen, A Bachhuka, S Han, F Wei, S Lu… - ACS …, 2017 - ACS Publications
Osteoimmunomodulation has informed the importance of modulating a favorable
osteoimmune environment for successful materials-mediated bone regeneration …

3D spatiotemporal mechanical microenvironment: a hydrogel‐based platform for guiding stem cell fate

Y Ma, M Lin, G Huang, Y Li, S Wang, G Bai… - Advanced …, 2018 - Wiley Online Library
Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …

Rheological properties of coordinated physical gelation and chemical crosslinking in gelatin methacryloyl (GelMA) hydrogels

AT Young, OC White, MA Daniele - Macromolecular bioscience, 2020 - Wiley Online Library
Synthetically modified proteins, such as gelatin methacryloyl (GelMA), are growing in
popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can …

Creating stiffness gradient polyvinyl alcohol hydrogel using a simple gradual freezing–thawing method to investigate stem cell differentiation behaviors

TH Kim, DB An, SH Oh, MK Kang, HH Song, JH Lee - Biomaterials, 2015 - Elsevier
Polyvinyl alcohol (PVA) cylindrical hydrogel with a stiffness gradient was prepared using a
simple liquid nitrogen (LN 2)-contacting gradual freezing and thawing method in order to …

Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer

NF Truong, E Kurt, N Tahmizyan, SC Lesher-Pérez… - Acta biomaterialia, 2019 - Elsevier
Designing scaffolds for polyplex-mediated therapeutic gene delivery has a number of
applications in regenerative medicine, such as for tissue repair after wounding or disease …