Infrared nanosensors of piconewton to micronewton forces

N Fardian-Melamed, A Skripka, B Ursprung, C Lee… - Nature, 2025 - nature.com
Mechanical force is an essential feature for many physical and biological processes,,,,,–,
and remote measurement of mechanical signals with high sensitivity and spatial resolution …

Collective mechanics of small migrating cell groups

W Shi, S Gupta, C Copos, A Mogilner - Seminars in Cell & Developmental …, 2025 - Elsevier
Migration of adhesive cell groups is a fundamental part of wound healing, development and
carcinogenesis. Intense research has been conducted on mechanisms of collective …

Interplay between Notch signaling and mechanical forces during developmental patterning processes

S Kasirer, D Sprinzak - Current Opinion in Cell Biology, 2024 - Elsevier
The coordination between biochemical signals and cell mechanics has emerged in recent
years as a crucial mechanism driving developmental patterning processes across a variety …

Mechanics of human embryo compaction

J Firmin, N Ecker, D Rivet Danon, Ö Özgüç… - Nature, 2024 - nature.com
The sha** of human embryos begins with compaction, during which cells come into close
contact,. Assisted reproductive technology studies indicate that human embryos fail …

Characterizing Cellular Physiological States with Three-Dimensional Shape Descriptors for Cell Membranes

G Guan, Y Chen, H Wang, Q Ouyang, C Tang - Membranes, 2024 - mdpi.com
The shape of a cell as defined by its membrane can be closely associated with its
physiological state. For example, the irregular shapes of cancerous cells and elongated …

CShaperApp: Segmenting and analyzing cellular morphologies of the develo** Caenorhabditis elegans embryo

J Cao, L Hu, G Guan, Z Li, Z Zhao, C Tang… - Quantitative …, 2024 - Wiley Online Library
Caenorhabditis elegans has been widely used as a model organism in developmental
biology due to its invariant development. In this study, we developed a desktop software …

Mechanical characterization of regenerating Hydra tissue spheres

T Perros, A Biquet-Bisquert, ZB Meriem, M Delarue… - Biophysical …, 2024 - cell.com
Hydra vulgaris, long known for its remarkable regenerative capabilities, is also a long-
standing source of inspiration for models of spontaneous patterning. Recently it became …

A computational pipeline for spatial mechano-transcriptomics

A Hallou, R He, BD Simons, B Dumitrascu - bioRxiv, 2023 - biorxiv.org
Advances in spatial profiling technologies are providing insights into how molecular
programs are influenced by local signaling and environmental cues. However, cell fate …

Image-based force inference by biomechanical simulation

M Vanslambrouck, W Thiels, J Vangheel… - PLOS Computational …, 2024 - journals.plos.org
During morphogenesis, cells precisely generate forces that drive cell shape changes and
cellular motion. These forces predominantly arise from contractility of the actomyosin cortex …

Graph topological transformations in space-filling cell aggregates

T Sarkar, M Krajnc - PLoS computational biology, 2024 - journals.plos.org
Cell rearrangements are fundamental mechanisms driving large-scale deformations of living
tissues. In three-dimensional (3D) space-filling cell aggregates, cells rearrange through …