Divergent Synthesis of Quinazolin-4(3H)-ones and Tryptanthrins Enabled by a tert-Butyl Hydroperoxide/K3PO4-Promoted Oxidative Cyclization of Isatins at Room …
FC Jia, ZW Zhou, C Xu, YD Wu, AX Wu - Organic letters, 2016 - ACS Publications
A synergetic tert-butyl hydroperoxide/K3PO4-promoted oxidative cyclization has been
developed for the facile synthesis of various functionalized quinazolin-4 (3 H)-ones from …
developed for the facile synthesis of various functionalized quinazolin-4 (3 H)-ones from …
Visible‐Light‐Induced Aerobic Intramolecular Cyclization of (2‐Aminophenyl)(1H‐indol‐1‐yl)methanones: Direct Access to Bioactive Tryptanthrin and its Derivatives
M Arockiaraj, G Singh, S Sree Marupalli… - Advanced Synthesis …, 2023 - Wiley Online Library
Visible‐light‐induced mild, transition metal, base, and photocatalyst‐free green protocol has
been developed for the synthesis of tryptanthrin and its derivatives. The present reaction is …
been developed for the synthesis of tryptanthrin and its derivatives. The present reaction is …
Divergent Synthesis of Methylisatoid and Tryptanthrin Derivatives by Ph3P–I2-Mediated Reaction of Isatins with and without Alcohols
M Pattarawarapan, N Wiriya… - The Journal of …, 2020 - ACS Publications
A novel phosphonium-mediated reaction of isatins is described. In the presence of alcohol,
the reaction proceeds to furnish C-12 modified tryptanthrin derivatives. Without alcohol, self …
the reaction proceeds to furnish C-12 modified tryptanthrin derivatives. Without alcohol, self …
Visible Light‐Induced Radical‐Radical Coupling: One‐Pot Synthesis of 6‐Benzyl‐6‐hydroxyindolo[2,1‐b]quinazolin‐12(6H)‐ones from Isatins and Potassium …
LQ Huang, CL Dong, YH He… - Advanced Synthesis & …, 2022 - Wiley Online Library
A method for one‐pot synthesis of 6‐benzyl‐6‐hydroxyindolo [2, 1‐b] quinazolin‐12 (6H)‐
ones from isatins and potassium benzyl trifluoroborates was developed. Bioactive …
ones from isatins and potassium benzyl trifluoroborates was developed. Bioactive …
Biological activity of quinazolinones
The chemical structure of quinazolinones includes benzene ring fused with 2-pyrimidinone
(1), 4-pyrimidinone (2) or 2, 4-pyrimidinedione (3) ring, and are named as quinazolin-2 (1H) …
(1), 4-pyrimidinone (2) or 2, 4-pyrimidinedione (3) ring, and are named as quinazolin-2 (1H) …
Conversion of isatins to tryptanthrins, heterocycles endowed with a myriad of bioactivities
R Amara, H Awad, D Chaker… - European Journal of …, 2019 - Wiley Online Library
The numerous bioactivities exhibited by tryptanthrins led chemists to develop synthetic
approaches towards this important scaffold. In particular, conversion of isatins into …
approaches towards this important scaffold. In particular, conversion of isatins into …
Photoredox‐Catalyzed Isatin Reactions: Access to Dibenzo‐1, 7‐Naphthyridine Carboxylate and Tryptanthrin
A procedure for the synthesis of dibenzo‐1, 7‐naphthyridine carboxylate by means of
photoredox catalysis has been developed. The reaction features an umpolung reaction of …
photoredox catalysis has been developed. The reaction features an umpolung reaction of …
Exploiting 1, 2, 3-triazolium ionic liquids for synthesis of tryptanthrin and chemoselective extraction of copper (II) ions and histidine-containing peptides
HY Li, CY Chen, HT Cheng, YH Chu - Molecules, 2016 - mdpi.com
Based on a common structural core of 4, 5, 6, 7-tetrahydro [1, 2, 3] triazolo [1, 5-a] pyridine, a
number of bicyclic triazolium ionic liquids 1–3 were designed and successfully prepared. In …
number of bicyclic triazolium ionic liquids 1–3 were designed and successfully prepared. In …
Spectro-luminescent characterization of molecular complex based on tryptanthrin for design of new effective drugs
Optical absorption (at room temperature), fluorescence (at room temperature and T= 78 K)
and phosphorescence (at T= 78 K) spectra of solution of the molecular complex based on …
and phosphorescence (at T= 78 K) spectra of solution of the molecular complex based on …
Biocatalyst mediated synthesis of tryptanthrins performed under ultrasonication
The concomitant exploitation of two of the green chemistry tools viz., sonication and
biocatalysis is reported here for the synthesis of natural alkaloid, tryptanthrin (indolo [2, 1‐b] …
biocatalysis is reported here for the synthesis of natural alkaloid, tryptanthrin (indolo [2, 1‐b] …