Myrsinane-type diterpenes: A comprehensive review on structural diversity, chemistry and biological activities

E Mendes, C Ramalhete, N Duarte - International Journal of Molecular …, 2023 - mdpi.com
Euphorbia species are important sources of polycyclic and macrocyclic diterpenes, which
have been the focus of natural-product-based drug research due to their relevant biological …

[HTML][HTML] Beyond Essential Oils: Diterpenes, Lignans, and Biflavonoids from Juniperus communis L. as a Source of Multi-Target Lead Compounds

AA Jojić, S Liga, D Uţu, G Ruse, L Suciu, A Motoc… - Plants, 2024 - mdpi.com
Common Juniper (Juniperus communis L.) is a gymnosperm that stands out through its
fleshy, spherical female cones, often termed simply “berries”. The cone berries and various …

Constructing a green oleaginous yeast cell factory for sustainable production of the plant-derived diterpenoid sclareol

ML Sun, Y Han, X Yu, K Wang, L Lin… - Green …, 2024 - pubs.rsc.org
Diterpenoids are an important class of secondary metabolites in nature with diverse
applications such as pharmaceuticals, flavors and fragrances. Sclareol, a plant-derived …

Z/E configuration controlled by a Taxus sesquiterpene synthase facilitating the biosynthesis of (3Z, 6E)-α-farnesene

X Tang, XJ Zhang, JF Pan, K Guo, CL Tan, QZ Zhang… - Phytochemistry, 2025 - Elsevier
Plant enzymes often present advantages in the synthesis of natural products with specific
configurations. Farnesene is a pharmacologically active sesquiterpene with three natural …

[HTML][HTML] Exploring the therapeutic potential of diterpenes in gastric cancer: Mechanisms, efficacy, and clinical prospects

C Ma, L Gao, K Song, B Gu, B Wang… - Biomolecules and …, 2025 - pmc.ncbi.nlm.nih.gov
Gastric cancer (GC) remains a significant global health challenge, particularly prevalent in
East Asia. Despite advancements in various treatment modalities, the prognosis for patients …

Mining novel terpene synthases from large-scale repositories

T Čalounová - 2024 - dspace.cuni.cz
Terpenes and terpenoids represent the largest and most structurally diverse group of natural
products, with applications across many fields, including the pharmaceutical industry. These …

[CITATION][C] Engineering synthetic regulatory circuits for precise metabolic control inSaccharomyces cerevisiae

Z Lu - 2024 - espace.library.uq.edu.au
Biomanufacturing through precision fermentation is revolutionising traditional methods of
chemical synthesis that rely on the petroleum industry and the extraction of plant materials …