Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

The cognitive model of depression has significantly influenced the understanding of
distorted cognitive processes in major depression; however, this model's conception of …

Importance Chronic back pain (CBP) is a leading cause of disability, and treatment is often
ineffective. Approximately 85% of cases are primary CBP, for which peripheral etiology …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for develo** …

Expectations are a central maintaining mechanism in mental disorders and most
psychological treatments aim to directly or indirectly modify clinically relevant expectations …

Fig. 1. Use cases for functional MRI (fMRI) biomarkers and an example of test-retest
reliability. Among the seven major categories of biomarkers defined by the US Food and …

Belief updating is a relatively nascent field of research that examines how people adjust
their beliefs in light of new evidence. So far, belief updating has been investigated in partly …

Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …

Since noxious stimulation usually leads to the perception of pain, pain has traditionally been
considered sensory nociception. But its variability and sensitivity to a broad array of …

Over the past decade, the mechanisms underlying placebo effects have begun to be
identified. At the same time, the placebo response appears to have increased in …