Recent findings in the regulation of G6PD and its role in diseases
Q Meng, Y Zhang, S Hao, H Sun, B Liu… - Frontiers in …, 2022 - frontiersin.org
Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the
pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP …
pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP …
Oncogenic KRAS induces NIX-mediated mitophagy to promote pancreatic cancer
Activating KRAS mutations are found in nearly all cases of pancreatic ductal
adenocarcinoma (PDAC), yet effective clinical targeting of oncogenic KRAS remains elusive …
adenocarcinoma (PDAC), yet effective clinical targeting of oncogenic KRAS remains elusive …
Isotope-assisted metabolic flux analysis: a powerful technique to gain new insights into the human metabolome in health and disease
Cell metabolism represents the coordinated changes in genes, proteins, and metabolites
that occur in health and disease. The metabolic fluxome, which includes both intracellular …
that occur in health and disease. The metabolic fluxome, which includes both intracellular …
Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells
13C metabolic flux analysis (MFA) is the most comprehensive means of characterizing
cellular metabolic states. Uniquely labeled isotopic tracers enable more focused analyses to …
cellular metabolic states. Uniquely labeled isotopic tracers enable more focused analyses to …
Genotype-specific responses in Atlantic salmon (Salmo salar) subject to dietary fish oil replacement by vegetable oil: a liver transcriptomic analysis
Background Expansion of aquaculture is seriously limited by reductions in fish oil (FO)
supply for aquafeeds. Terrestrial alternatives such as vegetable oils (VO) have been …
supply for aquafeeds. Terrestrial alternatives such as vegetable oils (VO) have been …
Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice
MH Oosterveer, A Grefhorst, TH van Dijk… - Journal of Biological …, 2009 - ASBMB
A growing body of evidence indicates that peroxisome proliferator-activated receptor α
(PPARα) not merely serves as a transcriptional regulator of fatty acid catabolism but also …
(PPARα) not merely serves as a transcriptional regulator of fatty acid catabolism but also …
Differential gene expression after total replacement of dietary fish meal and fish oil by plant products in rainbow trout (Oncorhynchus mykiss) liver
S Panserat, GA Hortopan, E Plagnes-Juan, C Kolditz… - Aquaculture, 2009 - Elsevier
Our objective was to analyse the hepatic transcriptomes of juvenile rainbow trout fed with a
plant-based diet. We focused our analysis on the total replacement of fish meal (FM) and fish …
plant-based diet. We focused our analysis on the total replacement of fish meal (FM) and fish …
Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells
TA Murphy, CV Dang, JD Young - Metabolic engineering, 2013 - Elsevier
We assessed several methods of 13C metabolic flux analysis (MFA) and found that
isotopically nonstationary MFA achieved maximum flux resolution in cultured P493-6 B-cells …
isotopically nonstationary MFA achieved maximum flux resolution in cultured P493-6 B-cells …
Experimental evidence and isotopomer analysis of mixotrophic glucose metabolism in the marine diatom Phaeodactylum tricornutum
Background Heterotrophic fermentation using simple sugars such as glucose is an
established and cost-effective method for synthesizing bioproducts from bacteria, yeast and …
established and cost-effective method for synthesizing bioproducts from bacteria, yeast and …
Concurrent isotope‐assisted metabolic flux analysis and transcriptome profiling reveal responses of poplar cells to altered nitrogen and carbon supply
X Zhang, A Misra, S Nargund, GD Coleman… - The Plant …, 2018 - Wiley Online Library
Reduced nitrogen is indispensable to plants. However, its limited availability in soil
combined with the energetic and environmental impacts of nitrogen fertilizers motivates …
combined with the energetic and environmental impacts of nitrogen fertilizers motivates …