In-line analysis of organ-on-chip systems with sensors: Integration, fabrication, challenges, and potential
S Fuchs, S Johansson, AØ Tjell, G Werr… - ACS Biomaterials …, 2021 - ACS Publications
Organ-on-chip systems are promising new in vitro research tools in medical,
pharmaceutical, and biological research. Their main benefit, compared to standard cell …
pharmaceutical, and biological research. Their main benefit, compared to standard cell …
Technical feasibility and physiological relevance of hypoxic cell culture models
J Pavlacky, J Polak - Frontiers in endocrinology, 2020 - frontiersin.org
Hypoxia is characterized as insufficient oxygen delivery to tissues and cells in the body and
is prevalent in many human physiology processes and diseases. Thus, it is an attractive …
is prevalent in many human physiology processes and diseases. Thus, it is an attractive …
3D printed HUVECs/MSCs cocultures impact cellular interactions and angiogenesis depending on cell-cell distance
Vascularization is a crucial process during the growth and development of bone 1, yet it
remains one of the main challenges in the reconstruction of large bone defects. The use of in …
remains one of the main challenges in the reconstruction of large bone defects. The use of in …
One‐step generation of core–shell gelatin methacrylate (GelMA) microgels using a droplet microfluidic system
Gelatin methacrylate (GelMA) microgels are promising scaffolds for biological applications,
such as tissue engineering and drug screening. Solid‐like GelMA microgels are limited by …
such as tissue engineering and drug screening. Solid‐like GelMA microgels are limited by …
[HTML][HTML] Gut-on-Chip microphysiological systems: Latest advances in the integration of sensing strategies and adoption of mature detection mechanisms
Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted
extraordinary progress in Organ-on-Chip (OoC) technology, leading to the development of in …
extraordinary progress in Organ-on-Chip (OoC) technology, leading to the development of in …
Oxygen consumption rate of tumour spheroids during necrotic-like core formation
R Mukomoto, Y Nashimoto, T Terai, T Imaizumi… - Analyst, 2020 - pubs.rsc.org
Hypoxia is one of the major hallmarks of solid tumours and is associated with the poor
prognosis of various cancers. A multicellular aggregate, termed a spheroid, has been used …
prognosis of various cancers. A multicellular aggregate, termed a spheroid, has been used …
The current landscape of 3D in vitro tumor models: what cancer hallmarks are accessible for drug discovery?
D Rodenhizer, T Dean, E D'Arcangelo… - Advanced …, 2018 - Wiley Online Library
Cancer prognosis remains a lottery dependent on cancer type, disease stage at diagnosis,
and personal genetics. While investment in research is at an all‐time high, new drugs are …
and personal genetics. While investment in research is at an all‐time high, new drugs are …
Think outside the box: 3D bioprinting concepts for biotechnological applications–recent developments and future perspectives
F Krujatz, S Dani, J Windisch, J Emmermacher… - Biotechnology …, 2022 - Elsevier
Abstract 3D bioprinting–the fabrication of geometrically complex 3D structures from
biocompatible materials containing living cells using additive manufacturing technologies–is …
biocompatible materials containing living cells using additive manufacturing technologies–is …
Transcriptional landscape of 3D vs. 2D ovarian cancer cell models
Simple Summary Ovarian cancer is one of the most lethal female cancers. Numerous
investigations into the development and progression of this disease have resulted in the …
investigations into the development and progression of this disease have resulted in the …
Biosensors to monitor cell activity in 3D hydrogel-based tissue models
Three-dimensional (3D) culture models have gained relevant interest in tissue engineering
and drug discovery owing to their suitability to reproduce in vitro some key aspects of human …
and drug discovery owing to their suitability to reproduce in vitro some key aspects of human …