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[HTML][HTML] Molecular mechanisms and applications of N-acyl homoserine lactone-mediated quorum sensing in bacteria
Microbial biodiversity includes biotic and abiotic components that support all life forms by
adapting to environmental conditions. Climate change, pollution, human activity, and natural …
adapting to environmental conditions. Climate change, pollution, human activity, and natural …
[HTML][HTML] Quorum quenching: a drug discovery approach against Pseudomonas aeruginosa
Pseudomonas aeruginosa, a ubiquitous opportunistic and nosocomial biofilm-forming
pathogen with complex, interconnected and hierarchical nature of QS systems (Las, Rhl …
pathogen with complex, interconnected and hierarchical nature of QS systems (Las, Rhl …
In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)
The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV)
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex …
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex …
Pseudomonas aeruginosa Biofilm Formation and Its Control
Microbes are hardly seen as planktonic species and are most commonly found as biofilm
communities in cases of chronic infections. Biofilms are regarded as a biological condition …
communities in cases of chronic infections. Biofilms are regarded as a biological condition …
Abiotic Small Molecule Inhibitors and Activators of the LasR Quorum Sensing Receptor in Pseudomonas aeruginosa with Potencies Comparable or Surpassing N …
DE Manson, GE Ananiev, S Guo… - ACS infectious …, 2024 - ACS Publications
The opportunistic pathogen Pseudomonas aeruginosa controls almost 10% of its genome,
including myriad virulence genes, via a cell-to-cell chemical communication system called …
including myriad virulence genes, via a cell-to-cell chemical communication system called …
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis
Bacteria communicate with each other using quorum sensing (QS) which works in an
inducer/receptor manner. QS plays the main role in orchestrating diverse bacterial virulence …
inducer/receptor manner. QS plays the main role in orchestrating diverse bacterial virulence …
In vivo, in vitro and molecular docking studies reveal the anti-virulence property of hispidulin against Pseudomonas aeruginosa through the modulation of quorum …
Pseudomonas aeruginosa is an audacious infectious agent involved in multiple persistent
and incurable diseases in hosts through quorum sensing mediated pathways. Thus …
and incurable diseases in hosts through quorum sensing mediated pathways. Thus …
[HTML][HTML] Virtual Screening of FDA-Approved Drugs against LasR of Pseudomonas aeruginosa for Antibiofilm Potential
Pseudomonas aeruginosa is a Gram-negative pathogenic bacterium that is present
commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary …
commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary …
High-Throughput Virtual Screening for a New Class of Antagonist Targeting LasR of Pseudomonas aeruginosa
A Vetrivel, S Natchimuthu, V Subramanian… - ACS …, 2021 - ACS Publications
Pseudomonas aeruginosa, an opportunistic human pathogen, causes fatal effects in
patients with cystic fibrosis and immunocompromised individuals and leads to around 1000 …
patients with cystic fibrosis and immunocompromised individuals and leads to around 1000 …
Computational discovery of plant-based inhibitors against human carbonic anhydrase IX and molecular dynamics simulation
Carbonic anhydrase IX (hCAIX) is a membrane-spanning metalloenzyme, encoded by CA9
gene, which can lead to various carcinomas if upregulated. Due to its overexpression in …
gene, which can lead to various carcinomas if upregulated. Due to its overexpression in …