Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Background: Neuronal-and circuit-level abnormalities of excitation and inhibition are shown
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …

Electrophysiology provides a real-time readout of neural functions and network capability in
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …

Healthy aging is associated with impairment in cognitive information processing. Several
neuroimaging methods such as functional magnetic resonance imaging, positron emission …

We studied resting-state oscillatory connectivity using magnetoencephalography in healthy
young humans (N= 183) genotyped for APOE-ɛ4, the greatest genetic risk for Alzheimer's …

Neural synchrony is intricately balanced in the normal resting brain but becomes altered in
Alzheimer's disease (AD). To determine the neurophysiological manifestations associated …

Epidemiologic and biologic studies support a link between type 2 diabetes mellitus and
Alzheimer's disease, but the precise mechanism linking the two remains unclear. Growing …

Amyloid-β (Aβ) deposition is known to starts decades before the onset of clinical symptoms
of Alzheimer's disease (AD), however, the detailed pathophysiological processes underlying …

Current biomarkers used in research and in clinical practice in Alzheimer's Disease (AD) are
the analysis of cerebral spinal fluid (CSF) to detect levels of Aβ42 and phosphorylated-tau …