Proteomics: technologies and their applications

B Aslam, M Basit, MA Nisar, M Khurshid… - Journal of …, 2016 - academic.oup.com
Proteomics involves the applications of technologies for the identification and quantification
of overall proteins present content of a cell, tissue or an organism. It supplements the other …

[HTML][HTML] The food metabolome: a window over dietary exposure

A Scalbert, L Brennan, C Manach… - The American journal of …, 2014 - Elsevier
The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With> 25,000 …

ProteomicsDB

T Schmidt, P Samaras, M Frejno… - Nucleic acids …, 2018 - academic.oup.com
Abstract ProteomicsDB (https://www. ProteomicsDB. org) is a protein-centric in-memory
database for the exploration of large collections of quantitative mass spectrometry-based …

A survey of computational methods and error rate estimation procedures for peptide and protein identification in shotgun proteomics

AI Nesvizhskii - Journal of proteomics, 2010 - Elsevier
This manuscript provides a comprehensive review of the peptide and protein identification
process using tandem mass spectrometry (MS/MS) data generated in shotgun proteomic …

Making proteomics data accessible and reusable: current state of proteomics databases and repositories

Y Perez‐Riverol, E Alpi, R Wang, H Hermjakob… - …, 2015 - Wiley Online Library
Compared to other data‐intensive disciplines such as genomics, public deposition and
storage of MS‐based proteomics, data are still less developed due to, among other reasons …

Bioinformatic analysis of proteomics data

A Schmidt, I Forne, A Imhof - BMC systems biology, 2014 - Springer
Most biochemical reactions in a cell are regulated by highly specialized proteins, which are
the prime mediators of the cellular phenotype. Therefore the identification, quantitation and …

Leveraging multilayered “omics” data for atopic dermatitis: a road map to precision medicine

D Ghosh, JA Bernstein, GK Khurana Hershey… - Frontiers in …, 2018 - frontiersin.org
Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects~ 280
million people worldwide. About 85% of AD cases begin in childhood, a significant portion of …

Advances in porcine genomics and proteomics—a toolbox for develo** the pig as a model organism for molecular biomedical research

E Bendixen, M Danielsen, K Larsen… - Briefings in functional …, 2010 - academic.oup.com
Our current knowledge of human biology is often based on studying a wide range of animal
species. In particular, for understanding human diseases, the development of adequate …

Conserved peptide fragmentation as a benchmarking tool for mass spectrometers and a discriminating feature for targeted proteomics

UH Toprak, LC Gillet, A Maiolica, P Navarro… - Molecular & Cellular …, 2014 - ASBMB
Quantifying the similarity of spectra is an important task in various areas of spectroscopy, for
example, to identify a compound by comparing sample spectra to those of reference …

[HTML][HTML] Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer

B Bueschbell, AB Caniceiro, PMS Suzano… - Drug Resistance …, 2022 - Elsevier
Globally with over 10 million deaths per year, cancer is the most transversal disease across
countries, cultures, and ethnicities, affecting both developed and develo** regions …