Data-driven decision-making for precision diagnosis of digestive diseases
S Jiang, T Wang, KH Zhang - BioMedical Engineering Online, 2023 - Springer
Modern omics technologies can generate massive amounts of biomedical data, providing
unprecedented opportunities for individualized precision medicine. However, traditional …
unprecedented opportunities for individualized precision medicine. However, traditional …
A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus
Hydrocephalus, characterized by cerebral ventriculomegaly, is the most common disorder
requiring brain surgery in children. Recent studies have implicated SMARCC1, a component …
requiring brain surgery in children. Recent studies have implicated SMARCC1, a component …
Familial and syndromic forms of arachnoid cyst implicate genetic factors in disease pathogenesis
HM Qureshi, KY Mekbib, G Allington… - Cerebral …, 2023 - academic.oup.com
Arachnoid cysts (ACs) are the most common space-occupying lesions in the human brain
and present significant challenges for clinical management. While most cases of ACs are …
and present significant challenges for clinical management. While most cases of ACs are …
Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics
Enlargement of the cerebrospinal fluid (CSF)–filled brain ventricles (cerebral
ventriculomegaly), the cardinal feature of congenital hydrocephalus (CH), is increasingly …
ventriculomegaly), the cardinal feature of congenital hydrocephalus (CH), is increasingly …
Identification of hub biomarkers and exploring the roles of immunity, M6A, ferroptosis, or cuproptosis in rats with diabetic erectile dysfunction
Y Wang, X Zhang, Y Chen, B Zhu, Q ** diseases for improving preventive measures, enabling precise …
Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis
D Zhao, J Zhuang, L Wang, L Wu, W Xu… - Journal of …, 2024 - Taylor & Francis
Purpose Septic cardiomyopathy (SCM) is a significant global public health concern
characterized by substantial morbidity and mortality, which has not been improved for …
characterized by substantial morbidity and mortality, which has not been improved for …
Prediction of Deleterious Single Amino Acid Polymorphisms with a Consensus Holdout Sampler
Background: Single Amino Acid Polymorphisms (SAPs) or nonsynonymous Single
Nucleotide Variants (nsSNVs) are the most common genetic variations. They result from …
Nucleotide Variants (nsSNVs) are the most common genetic variations. They result from …
Zebrafish navigating the metabolic maze: insights into human disease–assets, challenges and future implications
Zebrafish (Danio rerio) have become indispensable models for advancing our
understanding of multiple metabolic disorders such as obesity, diabetes mellitus …
understanding of multiple metabolic disorders such as obesity, diabetes mellitus …