Thermoresponsive surfaces for cell culture and enzyme-free cell detachment

AKAS Brun-Graeppi, C Richard, M Bessodes… - Progress in Polymer …, 2010 - Elsevier
Recently, there has been considerable interest in the development of materials whose
surface properties can be dynamically modulated by external stimuli. Stimuli-responsive …

Responsive systems for cell sheet detachment

NG Patel, G Zhang - Organogenesis, 2013 - Taylor & Francis
Cell sheet engineering has been progressing rapidly during the past few years and has
emerged as a novel approach for cell based therapy. Cell sheet harvest technology enables …

Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies

P Kumar, A Satyam, X Fan, E Collin, Y Rochev… - Scientific reports, 2015 - nature.com
Therapeutic strategies based on the principles of tissue engineering by self-assembly put
forward the notion that functional regeneration can be achieved by utilising the inherent …

Thermo-responsive hydrogel layers imprinted with RGDS peptide: a system for harvesting cell sheets.

G Pan, Q Guo, Y Ma, H Yang… - Angewandte Chemie …, 2013 - search.ebscohost.com
The article offers information on the introduction of the cell adhesive peptide Arg-Gly-Asp-
Ser (RGDS) onto a thermo-responsive cell culture substrate which was used as a novel …

Cytotoxicity and bioadhesive properties of poly-N-isopropylacrylamide hydrogel

V Capella, RE Rivero, AC Liaudat, LE Ibarra, DA Roma… - Heliyon, 2019 - cell.com
Several hydrogel surfaces present properties that simulate the mechanical and
physicochemical features of extracellular matrix (ECM), providing a platform that mimic the …

Cell and cell sheet recovery from pNIPAm coatings; motivation and history to present day approaches

ME Nash, D Healy, WM Carroll, C Elvira… - Journal of Materials …, 2012 - pubs.rsc.org
The regeneration of cells and cell sheets mediated by thermoresponsive substrates
represents an important and ever growing area in tissue engineering. This review seeks to …

Accelerated development of supramolecular corneal stromal-like assemblies from corneal fibroblasts in the presence of macromolecular crowders

P Kumar, A Satyam, X Fan, Y Rochev… - … Engineering Part C …, 2015 - liebertpub.com
Tissue engineering by self-assembly uses the cells' secretome as a regeneration template
and biological factory of trophic factors. Despite the several advantages that have been …

Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery

J Zhang, A Skardal, GD Prestwich - Biomaterials, 2008 - Elsevier
An unmet need for expansion of primary cells and progenitor cells in three dimensions (3-D)
is a synthetic mimic of the extracellular matrix (ECM) with user-controllable composition that …

[HTML][HTML] Synthesis and evaluation of thermoresponsive renewable lipid-based block copolymers for drug delivery

H Wang, A Ullah - Polymers, 2022 - mdpi.com
Polymeric micelle forming from self-assembly of amphiphilic macromolecules is one of the
most potent drug delivery systems. Fatty acids, naturally occurring hydrophobic lipid …

Straightforward, one-step fabrication of ultrathin thermoresponsive films from commercially available pNIPAm for cell culture and recovery

ME Nash, WM Carroll, N Nikoloskya… - … applied materials & …, 2011 - ACS Publications
The use of thermoresponsive surfaces as platforms for cell culture and cell regeneration has
been explored over the last couple of decades. Poly-N-isopropylacrylamide (pNIPAm) is a …