All mammalian uteri contain glands in the endometrium that synthesize or transport and
secrete substances essential for survival and development of the conceptus (embryo/fetus …

All mammalian uteri contain glands in the endometrium that synthesize or transport and
secrete substances essential for survival and development of the conceptus (embryo/fetus …

Many epithelial surfaces of the body are covered with protective mucus, and disrupted
mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection …

Inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease
(COPD) exhibit stereotyped traits that are variably expressed in each person. In …

Background: In asthma and chronic obstructive pulmonary disease (COPD), airway mucus
hypersecretion contributes to impaired mucociliary clearance, mucostasis and, potentially …

Airway mucus hypersecretion is a pathophysiological feature of asthma and chronic
obstructive pulmonary disease (COPD). The hypersecretion is associated with phenotypic …

CLCA1 is a member of the CLCA (calcium-activated chloride channel regulator) family and
plays an essential role in goblet cell mucus production from the respiratory tract epithelium …

Asthma exacerbations can be triggered by viral infections or allergens. The Th2 cytokines IL-
13 and IL-4 are produced during allergic responses and cause increases in airway epithelial …

Excessive mucus production is an important pathological feature of asthma. The Th2
cytokines IL-4 and IL-13 have both been implicated in allergen-induced mucus production …

The mucociliary system, consisting of mucus-secreting goblet cells and ciliated cells,
generates a constant overturning layer of protective mucus that lines the airway epithelium …