[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Recent advances in anti-virulence therapeutic strategies with a focus on dismantling bacterial membrane microdomains, toxin neutralization, quorum-sensing …

O Fleitas Martínez, MH Cardoso, SM Ribeiro… - Frontiers in cellular …, 2019 - frontiersin.org
Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …

Interference in bacterial quorum sensing: a biopharmaceutical perspective

B Rémy, S Mion, L Plener, M Elias… - Frontiers in …, 2018 - frontiersin.org
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

Quorum quenching: role in nature and applied developments

C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …

Quorum sensing inhibitors as antipathogens: biotechnological applications

VC Kalia, SKS Patel, YC Kang, JK Lee - Biotechnology advances, 2019 - Elsevier
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …

Bacterial quorum sensing during infection

S Azimi, AD Klementiev, M Whiteley… - Annual review of …, 2020 - annualreviews.org
Bacteria are highly interactive and possess an extraordinary repertoire of intercellular
communication and social behaviors, including quorum sensing (QS). QS has been studied …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - journals.asm.org
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

The multiple signaling systems regulating virulence in Pseudomonas aeruginosa

P Nadal Jimenez, G Koch, JA Thompson… - Microbiology and …, 2012 - journals.asm.org
Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Indole as an intercellular signal in microbial communities

JH Lee, J Lee - FEMS microbiology reviews, 2010 - academic.oup.com
Bacteria can utilize signal molecules to coordinate their behavior to survive in dynamic
multispecies communities. Indole is widespread in the natural environment, as a variety of …

Quinolones: from antibiotics to autoinducers

S Heeb, MP Fletcher, SR Chhabra… - FEMS microbiology …, 2011 - academic.oup.com
Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …