DNA methylation in genes associated with the evolution of ageing and disease: A critical review

MT Mc Auley - Ageing Research Reviews, 2021 - Elsevier
Ageing is characterised by a physical decline in biological functioning which results in a
progressive risk of mortality with time. As a biological phenomenon, it is underpinned by the …

Translational perspective on the role of testosterone in sexual function and dysfunction

CA Podlasek, J Mulhall, K Davies… - The journal of sexual …, 2016 - academic.oup.com
Introduction The biological importance of testosterone is generally accepted by the medical
community; however, controversy focuses on its relevance to sexual function and the sexual …

Combined effects of organochlorine pesticides on type 2 diabetes mellitus: insights from endocrine disrupting effects of hormones

J Shi, D Wei, C Ma, J Geng, M Zhao, J Hou, W Huo… - Environmental …, 2024 - Elsevier
Association between organochlorine pesticides (OCPs) exposure and type 2 diabetes
mellitus (T2DM) remains contradictory, and the evidence is mostly focused on a single …

[HTML][HTML] Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics

L Cao, Q Kang, Y Tian - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Pesticide residues, resulting from agricultural practices, pose significant health and
environmental risks. This review synthesizes the current understanding of pesticide impacts …

[HTML][HTML] The role of sex steroid hormones in the pathophysiology and treatment of sarcopenia

YJ Kim, A Tamadon, HT Park, H Kim, SY Ku - Osteoporosis and Sarcopenia, 2016 - Elsevier
Sex steroids influence the maintenance and growth of muscles. Decline in androgens,
estrogens and progesterone by aging leads to the loss of muscular function and mass …

Correlation between insulin-induced estrogen receptor methylation and atherosclerosis

J Min, Z Weitian, C Peng, P Yan, Z Bo, W Yan… - Cardiovascular …, 2016 - Springer
Background Hyperinsulinemia and insulin resistance have been recently recognized as an
important cause of atherosclerosis. Clinical studies have also found that expression of the …

[HTML][HTML] Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development

KP Keil, LL Abler, J Laporta, HM Altmann, B Yang… - Developmental …, 2014 - Elsevier
Androgen receptor (AR) signaling initiates mouse prostate development by stimulating
prostate ductal bud formation and specifying bud patterns. Curiously, however, prostatic bud …

MicroRNA‐205 is associated with diabetes mellitus‐induced erectile dysfunction via down‐regulating the androgen receptor

Y Wen, G Liu, Y Zhang, H Li - Journal of cellular and molecular …, 2019 - Wiley Online Library
As a major class of regulatory genes in majority metazoans, microRNAs (miRs) play an
important role in various diseases including diabetes mellitus (DM). Lack of androgens has …

MicroRNAs as diagnostic biomarkers in diabetes male infertility: a systematic review

Z Latifi, S Nikanfar, R Khodavirdilou, SM Beirami… - Molecular Biology …, 2025 - Springer
This study conducts an in-depth review of the correlation between testis tissue changes and
circulating microRNAs (miRNA) in diabetes-induced male reproductive complications …

New insight into molecular and hormonal connection in andrology

D Francomano, V Sanguigni, P Capogrosso… - International Journal of …, 2021 - mdpi.com
Hormones and cytokines are known to regulate cellular functions in the testes. These
biomolecules induce a broad spectrum of effects on various level of spermatogenesis, and …