Cyclic di-GMP: second messenger extraordinaire
U Jenal, A Reinders, C Lori - Nature Reviews Microbiology, 2017 - nature.com
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …
Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …
Biofilm control by interfering with c-di-GMP metabolism and signaling
Biofilm formation and biofilm-induced biodeterioration of surfaces have deeply affected the
life of our community. Cyclic dimeric guanosine monophosphate (c-di-GMP) is a small …
life of our community. Cyclic dimeric guanosine monophosphate (c-di-GMP) is a small …
A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa
The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …
Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators
J Nesper, I Hug, S Kato, CS Hee, JM Habazettl… - Elife, 2017 - elifesciences.org
The flagellar motor is a sophisticated rotary machine facilitating locomotion and signal
transduction. Owing to its important role in bacterial behavior, its assembly and activity are …
transduction. Owing to its important role in bacterial behavior, its assembly and activity are …
Structural conservation and diversity of PilZ-related domains
MY Galperin, SH Chou - Journal of bacteriology, 2020 - Am Soc Microbiol
The widespread bacterial second messenger cyclic diguanylate (c-di-GMP) regulates a
variety of processes, including protein secretion, motility, cell development, and biofilm …
variety of processes, including protein secretion, motility, cell development, and biofilm …
Tetrameric PilZ protein stabilizes stator ring in complex flagellar motor and is required for motility in Campylobacter jejuni
Y Chen, S Tachiyama, Y Li, X Feng, H Zhao… - Proceedings of the …, 2025 - pnas.org
Rotation of the bacterial flagellum, the first identified biological rotary machine, is driven by
its stator units. Knowledge gained about the function of stator units has increasingly led to …
its stator units. Knowledge gained about the function of stator units has increasingly led to …
Cohesive Properties of the Caulobacter crescentus Holdfast Adhesin Are Regulated by a Novel c-di-GMP Effector Protein
KS Sprecher, I Hug, J Nesper, E Potthoff, MA Mahi… - MBio, 2017 - Am Soc Microbiol
When encountering surfaces, many bacteria produce adhesins to facilitate their initial
attachment and to irreversibly glue themselves to the solid substrate. A central molecule …
attachment and to irreversibly glue themselves to the solid substrate. A central molecule …
[HTML][HTML] Nucleotide second messengers in bacterial decision making
Highlights•Structural analysis of NSM regulators reveals new mechanisms of NSM
signalling.•NSM proteins binding multiple ligands support crosstalk between signalling …
signalling.•NSM proteins binding multiple ligands support crosstalk between signalling …
Biofilms 2015: multidisciplinary approaches shed light into microbial life on surfaces
The 7th ASM Conference on Biofilms was held in Chicago, Illinois, from 24 to 29 October
2015. The conference provided an international forum for biofilm researchers across …
2015. The conference provided an international forum for biofilm researchers across …