Cell-based biosensors: Recent trends, challenges and future perspectives

N Gupta, V Renugopalakrishnan, D Liepmann… - Biosensors and …, 2019 - Elsevier
Existing at the interface of biology and electronics, living cells have been in use as
biorecognition elements (bioreceptors) in biosensors since the early 1970s. They are an …

Unraveling the complex regulatory networks in biofilm formation in bacteria and relevance of biofilms in environmental remediation

KU Mahto, S Kumari, S Das - Critical Reviews in Biochemistry and …, 2022 - Taylor & Francis
Biofilms are assemblages of bacteria embedded within a matrix of extracellular polymeric
substances (EPS) attached to a substratum. The process of biofilm formation is a complex …

Tailored bacteria tackling with environmental mercury: Inspired by natural mercuric detoxification operons

C Hui, B Ma, S Hu, C Wu - Environmental Pollution, 2024 - Elsevier
Mercury (Hg) and its inorganic and organic compounds significantly threaten the ecosystem
and human health. However, the natural and anthropogenic Hg environmental inputs …

Quorum sensing communication: molecularly connecting cells, their neighbors, and even devices

S Wang, GF Payne, WE Bentley - Annual review of chemical …, 2020 - annualreviews.org
Quorum sensing (QS) is a molecular signaling modality that mediates molecular-based cell–
cell communication. Prevalent in nature, QS networks provide bacteria with a method to …

A test strip platform based on a whole-cell microbial biosensor for simultaneous on-site detection of total inorganic mercury pollutants in cosmetics without the need for …

M Guo, J Wang, R Du, Y Liu, J Chi, X He… - Biosensors and …, 2020 - Elsevier
Mercury pollutants such as mercuric chloride (HgCl 2), mercurous chloride (Hg 2 Cl 2) and
mercuric ammonium chloride (Hg (NH 2) Cl) are often found in cosmetics. Previous attempts …

Development of a bioavailable Hg (II) sensing system based on MerR-regulated visual pigment biosynthesis

Y Guo, C Hui, L Liu, M Chen, H Huang - Scientific Reports, 2021 - nature.com
Engineered microorganisms have proven to be a highly effective and robust tool to
specifically detect heavy metals in the environment. In this study, a highly specific pigment …

Genetic control of violacein biosynthesis to enable a pigment-based whole-cell lead biosensor

C Hui, Y Guo, L Liu, N Zhang, C Gao, X Yang, J Yi - RSC advances, 2020 - pubs.rsc.org
Environmental risks continue to grow due to heavy metal contamination caused by
anthropogenic activities. Accumulation of harmful quantities of lead poses a threat to aquatic …

Engineered whole-cell-based biosensors: sensing environmental heavy metal pollutants in water—a review

S Kannappan, BCM Ramisetty - Applied Biochemistry and Biotechnology, 2022 - Springer
The frequent exposure and accumulation of heavy metals in organisms cause serious health
issues affecting a range of organs such as the brain, liver, and reproductive organs in adults …

Metabolic engineering of the carotenoid biosynthetic pathway toward a specific and sensitive inorganic mercury biosensor

C Hui, S Hu, L Li, J Yun, Y Zhang, J Yi, N Zhang… - RSC advances, 2022 - pubs.rsc.org
The toxicity of mercury (Hg) mainly depends on its form. Whole-cell biosensors respond
selectively to toxic Hg (II), efficiently transformed by environmental microbes into …

Indigoidine biosynthesis triggered by the heavy metal-responsive transcription regulator: a visual whole-cell biosensor

C Hui, Y Guo, L Li, L Liu, Y Chen, J Yi… - Applied Microbiology and …, 2021 - Springer
During the last few decades, whole-cell biosensors have attracted increasing attention for
their enormous potential in monitoring bioavailable heavy metal contaminations in the …