As an important reversible lipid modification, S-palmitoylation mainly occurs at specific
cysteine residues in proteins, participates in regulating various biological processes and is …

One of the key features of intrinsically disordered regions (IDRs) is their ability to interact
with a broad range of partner molecules. Multiple types of interacting IDRs were identified …

Understanding intracellular phase separation is crucial for deciphering transcriptional
control, cell fate transitions, and disease mechanisms. However, the key residues, which …

The Omicron variant has three subvariants: BA. 1 (B. 1.1. 529.1), BA. 2 (B. 1.1. 529.2), and
BA. 3 (B. 1.1. 529.3). BA. 2 is found to be able to alarmingly reinfect patients originally …

Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) is a free, one-stop
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …

Protein intrinsic disorder (ID) is a complex and context‐dependent phenomenon that covers
a continuum between fully disordered states and folded states with long dynamic regions …

Intrinsic disorder (ID) in proteins is well-established in structural biology, with increasing
evidence for its involvement in essential biological processes. As measuring dynamic ID …

Motivation Related to many important biological functions, intrinsically disordered regions
(IDRs) are widely distributed in proteins. Accurate prediction of IDRs is critical for the protein …

Lysine β-hydroxybutyrylation (Kbhb) is a post-translational modification induced by the
ketogenic diet (KD), a diet showing therapeutic effects on multiple human diseases. Little is …

A central tenet of biology is that globular proteins have a unique 3D structure under
physiological conditions. Recent work has challenged this notion by demonstrating that …