Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

The gut microbiota (GM) plays an important role in the physiology and pathology of the host.
Microbiota communicate with different organs of the organism by synthesizing hormones …

Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …