Diet and inflammation in cognitive ageing and Alzheimer's disease

AM McGrattan, B McGuinness, MC McKinley… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …

Imaging the role of inflammation in mood and anxiety-related disorders

JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

Inflammation effects on motivation and motor activity: role of dopamine

JC Felger, MT Treadway - Neuropsychopharmacology, 2017 - nature.com
Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Evidence for brain glial activation in chronic pain patients

ML Loggia, DB Chonde, O Akeju, G Arabasz, C Catana… - Brain, 2015 - academic.oup.com
Although substantial evidence has established that microglia and astrocytes play a key role
in the establishment and maintenance of persistent pain in animal models, the role of glial …

Healthy lifestyles and wellbeing reduce neuroinflammation and prevent neurodegenerative and psychiatric disorders

E Kip, LC Parr-Brownlie - Frontiers in Neuroscience, 2023 - frontiersin.org
Since the mid-20th century, Western societies have considered productivity and economic
outcomes are more important than focusing on people's health and wellbeing. This focus …

Microglial physiology: unique stimuli, specialized responses

RM Ransohoff, VH Perry - Annual review of immunology, 2009 - annualreviews.org
Microglia, the macrophages of the central nervous system parenchyma, have in the normal
healthy brain a distinct phenotype induced by molecules expressed on or secreted by …

SPECT and PET imaging in Alzheimer's disease

V Valotassiou, J Malamitsi, J Papatriantafyllou… - Annals of nuclear …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia. Beta-amyloid (Aβ) deposition and neurofibrillary tangles (NFTs) …

Inflammation, microglia, and Alzheimer's disease

B Cameron, GE Landreth - Neurobiology of disease, 2010 - Elsevier
Microglia are the brain's tissue macrophage and representative of the innate immune
system. These cells normally provide tissue maintenance and immune surveillance of the …

Neuroinflammation: modulation by flavonoids and mechanisms of action

JPE Spencer, K Vafeiadou, RJ Williams… - Molecular aspects of …, 2012 - Elsevier
Neuroinflammatory processes are known to contribute to the cascade of events culminating
in the neuronal damage that underpins neurodegenerative disorders such as Parkinson's …

The role of microglia and myeloid immune cells in acute cerebral ischemia

C Benakis, L Garcia-Bonilla, C Iadecola… - Frontiers in cellular …, 2015 - frontiersin.org
The immune response to acute cerebral ischemia is a major contributor to stroke
pathobiology. The inflammatory response is characterized by the participation of brain …