Vascular biology of hydrogen sulfide

NL Kanagy, C Szabo… - American Journal of …, 2017 - journals.physiology.org
Hydrogen sulfide (H2S) is a ubiquitous signaling molecule with important functions in many
mammalian organs and systems. Observations in the 1990s ascribed physiological actions …

[HTML][HTML] Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization

KÉ Sikura, Z Combi, L Potor, T Szerafin… - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Hydrogen sulfide (H 2 S) was revealed to inhibit aortic valve
calcification and inflammation was implicated in the pathogenesis of calcific aortic valve …

Hydrogen sulfide: a gaseous signaling molecule modulates tissue homeostasis: implications in ophthalmic diseases

Y Han, Q Shang, J Yao, Y Ji - Cell Death & Disease, 2019 - nature.com
Hydrogen sulfide (H2S) serves as a gasotransmitter in the regulation of organ development
and maintenance of homeostasis in tissues. Its abnormal levels are associated with multiple …

GYY4137, a novel water-soluble, H2S-releasing molecule

P Rose, BW Dymock, PK Moore - Methods in enzymology, 2015 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as the so called “third gasotransmitter” taking its
place alongside nitric oxide and carbon monoxide. In recent years, H 2 S has been reported …

GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats

G Meng, J Wang, Y **ao, W Bai, L **e… - Journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Hydrogen sulfide (H2S) is a gasotransmitter that regulates cardiovascular functions. The
present study aimed to determine the protective effect of slow-releasing H2S donor …

Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases

G Meng, Y Ma, L **e, A Ferro… - British journal of …, 2015 - Wiley Online Library
Hydrogen sulfide (H2S) has traditionally been viewed as a highly toxic gas; however, recent
studies have implicated H2S as a third member of the gasotransmitter family, exhibiting …

The Role of Hydrogen Sulfide and H2S-donors in Myocardial Protection Against Ischemia/Reperfusion Injury

V Citi, E Piragine, L Testai, MC Breschi… - Current medicinal …, 2018 - benthamdirect.com
Hydrogen sulfide (H2S), previously known only as a toxic agent, in the last decades has
been recognized as an important endogenous gasotransmitter, playing a key role in the …

Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis

H Zhang, Z Bai, L Zhu, Y Liang, X Fan, J Li… - European Journal of …, 2020 - Elsevier
Atherosclerosis (AS), an important cause of high mortality of cardiovascular disease,
involves numerous pathophysiological processes, including endothelial cell damage …

Hydrogen sulfide-induced vasodilation: the involvement of vascular potassium channels

XY Liu, LL Qian, RX Wang - Frontiers in pharmacology, 2022 - frontiersin.org
Hydrogen sulfide (H2S) has been highlighted as an important gasotransmitter in mammals.
A growing number of studies have indicated that H2S plays a key role in the …

Discovery of New H2S Releasing Phosphordithioates and 2,3-Dihydro-2-phenyl-2-sulfanylenebenzo[d][1,3,2]oxazaphospholes with Improved Antiproliferative …

W Feng, XY Teo, W Novera… - Journal of Medicinal …, 2015 - ACS Publications
Hydrogen sulfide (H2S) is now recognized as a physiologically important gasotransmitter.
Compounds which release H2S slowly are sought after for their potential in therapy. Herein …