[HTML][HTML] The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders

MK Tripathi, M Kartawy, H Amal - Redox Biology, 2020 - Elsevier
Nitric oxide (NO) is a multifunctional signalling molecule and a neurotransmitter that plays
an important role in physiological and pathophysiological processes. In physiological …

The contribution of an imbalanced redox signalling to neurological and neurodegenerative conditions

JR Steinert, H Amal - Free Radical Biology and Medicine, 2023 - Elsevier
Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …

[HTML][HTML] The nitric oxide (NO) donor sodium nitroprusside (SNP) and its potential for the schizophrenia therapy: lights and shadows

E Zoupa, N Pitsikas - Molecules, 2021 - mdpi.com
Schizophrenia is a severe psychiatric disorder affecting up to 1% of the worldwide
population. Available therapy presents different limits comprising lack of efficiency in …

Oxidative stress and nitric oxide in autism spectrum disorder and other neuropsychiatric disorders

K Yui, Y Kawasaki, H Yamada… - CNS & Neurological …, 2016 - benthamdirect.com
The etiology of autism spectrum disorder (ASD) remains unclear; however, the toxic
environmental exposure to oxidative stress has been suggested to play an important role in …

Pharmacological management of neurocognitive impairment in schizophrenia: A narrative review

K Arsenault‐Mehta, M Hochman‐Bérard… - …, 2024 - Wiley Online Library
Background Cognitive impairment are among the core features of schizophrenia,
experienced by up to 75% of patients. Available treatment options for schizophrenia …

New insights on nitric oxide: Focus on animal models of schizophrenia

JC Morales-Medina, P Aguilar-Alonso… - Behavioural Brain …, 2021 - Elsevier
Schizophrenia is a devastating complex disorder characterised by a constellation of
behavioral deficits with the underlying mechanisms not fully known. Nitric oxide (NO) has …

The role of nitric oxide donors in schizophrenia: Basic studies and clinical applications

N Pitsikas - European journal of pharmacology, 2015 - Elsevier
Schizophrenia is a complex and chronic mental health disease that affects nearly 1% of the
population worldwide. While the current antipsychotic medications have profoundly …

The effect of sodium nitroprusside on psychotic symptoms and spatial working memory in patients with schizophrenia: a randomized, double-blind, placebo-controlled …

JM Stone, PD Morrison, I Koychev, F Gao… - Psychological …, 2016 - cambridge.org
Background Sodium nitroprusside (SNP) has been reported to rapidly reduce psychotic
symptoms in patients with schizophrenia. This has the potential to revolutionize treatment for …

Efficacy and tolerability of adjunctive intravenous sodium nitroprusside treatment for outpatients with schizophrenia: a randomized clinical trial

HE Brown, O Freudenreich, X Fan, SO Heard… - JAMA …, 2019 - jamanetwork.com
Importance Antipsychotic medications for the treatment of schizophrenia have limitations,
and new treatments are needed. A prior pilot investigation suggested that adjunctive sodium …

Angiogenesis in the pathophysiology of schizophrenia—a comprehensive review and a conceptual hypothesis

R Lopes, R Soares, R Coelho, M Figueiredo-Braga - Life sciences, 2015 - Elsevier
Schizophrenia (SZ) is a severe mental disorder poorly elucidated from the etiopathogenesis
prism. Recently, several micro-and macro-vascular abnormalities have been consistently …