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Organic Bioelectronics for In Vitro Systems
Bioelectronics have made strides in improving clinical diagnostics and precision medicine.
The potential of bioelectronics for bidirectional interfacing with biology through continuous …
The potential of bioelectronics for bidirectional interfacing with biology through continuous …
Organ‐on‐a‐chip systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
Recent progress in translational engineered in vitro models of the central nervous system
The complexity of the human brain poses a substantial challenge for the development of
models of the CNS. Current animal models lack many essential human characteristics (in …
models of the CNS. Current animal models lack many essential human characteristics (in …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
Microphysiological human brain and neural systems-on-a-chip: potential alternatives to small animal models and emerging platforms for drug discovery and …
Translational challenges associated with reductionist modeling approaches, as well as
ethical concerns and economic implications of small animal testing, drive the need for …
ethical concerns and economic implications of small animal testing, drive the need for …
Integrating organs-on-chips: multiplexing, scaling, vascularization, and innervation
Organs-on-chips (OoCs) have attracted significant attention because they can be designed
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …
Functional connectivity in in vitro neuronal assemblies
Complex network topologies represent the necessary substrate to support complex brain
functions. In this work, we reviewed in vitro neuronal networks coupled to Micro-Electrode …
functions. In this work, we reviewed in vitro neuronal networks coupled to Micro-Electrode …
Three‐dimensional models of the human brain development and diseases
Deciphering the human brain pathophysiology remains one of the greatest challenges of the
21st century. Neurological disorders represent a significant proportion of diseases burden; …
21st century. Neurological disorders represent a significant proportion of diseases burden; …
The potential of in vitro neuronal networks cultured on micro electrode arrays for biomedical research
M Cerina, MC Piastra, M Frega - Progress in Biomedical …, 2023 - iopscience.iop.org
In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …
Modular microstructure design to build neuronal networks of defined functional connectivity
Theoretical and in vivo neuroscience research suggests that functional information transfer
within neuronal networks is influenced by circuit architecture. Due to the dynamic …
within neuronal networks is influenced by circuit architecture. Due to the dynamic …