Classically, the following three morphological states of microglia have been defined:
ramified, amoeboid and phagocytic. While ramified cells were long regarded as “resting” …

Exposure to acute and chronic stress has a broad range of structural effects on the brain.
The brain areas commonly targeted in the stress response models include the …

The metabolic and cardiovascular clinical manifestations in patients with Cushing's
syndrome (CS) are generally well known. However, recent studies have broadened the …

Increased life expectancy in combination with modern life style and high prevalence of
obesity are important risk factors for development of neurodegenerative diseases …

Glucocorticoid stress hormones are powerful modulators of brain function and can affect
mood and cognitive processes. The hippocampus is a prominent glucocorticoid target and …

Objective To test the hypothesis that systemic and inhaled glucocorticoid use is associated
with changes in grey matter volume (GMV) and white matter microstructure. Design Cross …

Glucocorticoids are powerful modulators of brain function. They act via mineralocorticoid
and glucocorticoid receptors (MR and GR). These are best understood as transcription …

Background Despite hypothalamus has long being considered to be involved in the
pathophysiology of cluster headache, the inconsistencies of previous neuroimaging studies …

Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme
form, Cushing's syndrome, is adequately modelled in the AdKO2. 0 mouse, consequential to …

Fetal programming is the concept that maternal stressors during critical periods of fetal
development can alter offspring phenotypes postnatally. Excess glucocorticoids can interact …