Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Ultrasound molecular imaging and its applications in cancer diagnosis and therapy

G Zhang, HR Ye, Y Sun, ZZ Guo - ACS sensors, 2022 - ACS Publications
Ultrasound imaging is regarded as a highly sensitive imaging modality used in routine
clinical examinations. Over the last several decades, ultrasound contrast agents have been …

Genomically mined acoustic reporter genes for real-time in vivo monitoring of tumors and tumor-homing bacteria

RC Hurt, MT Buss, M Duan, K Wong, MY You… - Nature …, 2023 - nature.com
Ultrasound allows imaging at a much greater depth than optical methods, but existing
genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor …

Nanoengineered neutrophils as a cellular sonosensitizer for visual sonodynamic therapy of malignant tumors

L Sun, J Zhou, T Luo, J Wang, L Kang… - Advanced …, 2022 - Wiley Online Library
The rapid evolution of cell‐based theranostics has attracted extensive attention due to their
unique advantages in biomedical applications. However, the inherent functions of cells …

Fluorescence, ultrasonic and photoacoustic imaging for analysis and diagnosis of diseases

B Chu, Z Chen, H Shi, X Wu, H Wang… - Chemical …, 2023 - pubs.rsc.org
Biomedical imaging technology, which allows us to peer deeply within living subjects and
visually explore the delivery and distribution of agents in living things, is producing …

Truly tiny acoustic biomolecules for ultrasound imaging and therapy

B Ling, B Gungoren, Y Yao, P Dutka… - Advanced …, 2024 - Wiley Online Library
Nanotechnology offers significant advantages for medical imaging and therapy, including
enhanced contrast and precision targeting. However, integrating these benefits into …

New insights for biosensing: Lessons from microbial defense systems

Y Wan, C Zong, X Li, A Wang, Y Li, T Yang… - Chemical …, 2022 - ACS Publications
Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy

Y Wu, Z Huang, Y Liu, P He, Y Wang, L Yan… - Nature …, 2024 - nature.com
There remains a critical need for the precise control of CRISPR (clustered regularly
interspaced short palindromic repeats)-based technologies. Here, we engineer a set of …

Gas Vesicle–Blood Interactions Enhance Ultrasound Imaging Contrast

B Ling, JH Ko, B Stordy, Y Zhang, TF Didden… - Nano Letters, 2023 - ACS Publications
Gas vesicles (GVs) are genetically encoded, air-filled protein nanostructures of broad
interest for biomedical research and clinical applications, acting as imaging and therapeutic …

SEMPER: Stoichiometric expression of mRNA polycistrons by eukaryotic ribosomes for compact, ratio-tunable multi-gene expression

M Duan, I Dev, A Lu, G Ayrapetyan, MY You… - Cell Systems, 2024 - cell.com
Here, we present a method for expressing multiple open reading frames (ORFs) from single
transcripts using the leaky scanning model of translation initiation. In this approach termed" …